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3374 reactions imported from Wikipedia named-reactions and Organic Syntheses archives. Filter by source or search by name + summary.

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Equation Name Summary Source
FLUORINATIONS WITH PYRIDINIUM POLYHYDROGEN FLUORIDE REAGENT: 1-FLUOROADAMANTANE (Tricyclo[3.3.1.13,7]decane, 1-fluoro-) Preparation of Tricyclo[3.3.1.13,7]decane, 1-fluoro-. Submitted by George A. Olah1 and Michael Watkins. DOI: 10.15227/orgsyn.058.0075. Organic Syntheses
FLUOROBENZENE (Benzene, fluoro-) Preparation of Benzene, fluoro-. Submitted by D. T. Flood. DOI: 10.15227/orgsyn.013.0046. Organic Syntheses
FORMAMIDINE ACETATE Preparation of FORMAMIDINE ACETATE. Submitted by Edward C. Taylor, Wendell A. Ehrhart, and M. Kawanisi1. DOI: 10.15227/orgsyn.046.0039. Organic Syntheses
FORMATION AND PHOTOCHEMICAL WOLFF REARRANGEMENT OF CYCLIC α-DIAZO KETONES: D-NORANDROST-5-EN-3β-OL-16-CARBOXYLIC ACIDS (D-Norandrost-5-ene-16-carboxylic acids, 3β-hydroxy-, (3β,16α) and (3β,16β)-) Rearrangement Preparation of D-Norandrost-5-ene-16-carboxylic acids, 3β-hydroxy-, (3β,16α) and (3β,16β)-. Submitted by Thomas N. Wheeler and J. Meinwald1. DOI: 10.15227/orgsyn.052.0053. Organic Syntheses
FORMATION OF γ-KETO ESTERS FROM β-KETO ESTERS: METHYL 5,5-DIMETHYL-4-OXOHEXANOATE (Hexanoic acid, 5,5-dimethyl-4-oxo-, methyl ester) Preparation of Hexanoic acid, 5,5-dimethyl-4-oxo-, methyl ester. Submitted by Matthew D. Ronsheim, Ramona K. Hilgenkamp, and Charles K. Zercher1. DOI: 10.15227/orgsyn.079.0146. Organic Syntheses
Formose reaction The formose reaction, discovered by Aleksandr Butlerov in 1861, and hence also known as the Butlerov reaction, involves the formation of sugars from formaldehyde. The term formose is a portmanteau of … Wikipedia: Category:Name reactions
FORMYL TRANSFER TO GRIGNARD REAGENTS WITH N-FORMYLPIPERIDINE: 3-PHENYLPROPIONALDEHYDE Organometallic addition Preparation of FORMYL TRANSFER TO GRIGNARD REAGENTS WITH N-FORMYLPIPERIDINE: 3-PHENYLPROPIONALDEHYDE. Submitted by George A. Olah and Massoud Arvanaghi1. DOI: 10.15227/orgsyn.064.0114. Organic Syntheses
Forster–Decker method The Forster–Decker method is a series of chemical reactions that have the effect of mono-alkylating a primary amine (1), forming a secondary amine (6). The process occurs by way of transient formation… Wikipedia: Category:Name reactions
FRAGMENTATION OF α,β-EPOXYKETONES TO ACETYLENIC ALDEHYDES AND KETONES: PREPARATION OF 2,3-EPOXYCYCLOHEXANONE AND ITS FRAGMENTATION TO 5-HEXYNAL (5-Hexynal) Preparation of 5-Hexynal. Submitted by Dorothee Felix, Claude Wintner, and A. Eschenmoser1. DOI: 10.15227/orgsyn.055.0052. Organic Syntheses
FRAGMENTATION-RECOMBINATION NAZAROV CYCLIZATION: 3,4-DIMETHYLCYCLOPENT-2-EN-1-ONE Cyclization Preparation of FRAGMENTATION-RECOMBINATION NAZAROV CYCLIZATION: 3,4-DIMETHYLCYCLOPENT-2-EN-1-ONE. Submitted by Keith D. Schwartz and James D. White1. DOI: 10.15227/orgsyn.083.0049. Organic Syntheses
Fráter–Seebach alkylation In organic chemistry, the Fráter–Seebach alkylation (also known as Seebach–Fráter alkylation or Fráter–Seebach reaction) is a diastereoselective alkylation of chiral beta-hydroxy esters using strong b… Wikipedia: Category:Name reactions
FREE-RADICAL ALKYLATION OF QUINONES: 2-PHENOXYMETHYL-1,4-BENZOQUINONE (2,5-Cyclohexadiene-1,4-dione, 2-(phenoxymethyl)-) Preparation of 2,5-Cyclohexadiene-1,4-dione, 2-(phenoxymethyl)-. Submitted by Niels Jacobsen1. DOI: 10.15227/orgsyn.056.0068. Organic Syntheses
FREE-RADICAL CYCLIZATION: ETHYL 1-CYANO-2-METHYLCYCLOHEXANECARBOXYLATE (Cyclohexanecarboxylic acid, 1-cyano-2-methyl-, ethyl ester) Cyclization Preparation of Cyclohexanecarboxylic acid, 1-cyano-2-methyl-, ethyl ester. Submitted by Marc Julia and Michel Maumy1. DOI: 10.15227/orgsyn.055.0057. Organic Syntheses
Friedel-Crafts acylation: benzene + acetyl chloride → acetophenone Scale Electrophilic aromatic substitution Textbook electrophilic aromatic substitution via the AlCl3-generated acylium ion. The product ketone (acetophenone) deactivates the ring toward further acylation, so unlike F-C alkylation, monoacylati… Friedel-Crafts 1877
Friedel–Crafts reaction The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring. Friedel–Crafts reactions are of two main types: al… Wikipedia: Category:Name reactions
Friedländer synthesis The Friedländer synthesis is a chemical reaction of 2-aminobenzaldehydes with ketones to form quinoline derivatives. It is named after German chemist Paul Friedländer (1857–1923). Wikipedia: Category:Name reactions
Fries rearrangement Rearrangement The Fries rearrangement, named for the German chemist Karl Theophil Fries, is a rearrangement reaction of a phenolic ester to a keto phenol. The reaction is induced by a Lewis acid. Wikipedia: Category:Name reactions
Fritsch–Buttenberg–Wiechell rearrangement Rearrangement The Fritsch–Buttenberg–Wiechell rearrangement, named for Paul Ernst Moritz Fritsch (1859–1913), Wilhelm Paul Buttenberg, and Heinrich G. Wiechell, is a chemical reaction whereby a 1,1-diaryl-2-bromo-a… Wikipedia: Category:Name reactions
Fujimoto–Belleau reaction The Fujimoto–Belleau reaction is a chemical reaction that forms cyclic α-substituted α,β-unsaturated ketones from enol lactones. The reaction was discovered in 1951 by George I. Fujimoto and Bernard B… Wikipedia: Category:Name reactions
Fujiwara–Moritani reaction In organic chemistry, the Fujiwara–Moritani reaction is a type of cross coupling reaction where an aromatic C-H bond is directly coupled to an olefinic C-H bond, generating a new C-C bond. This reacti… Wikipedia: Category:Name reactions
Fukuyama coupling Cross-coupling The Fukuyama coupling is a coupling reaction taking place between a thioester and an organozinc halide in the presence of a palladium catalyst. The reaction product is a ketone. This reaction was disc… Wikipedia: Category:Name reactions
Fukuyama indole synthesis The Fukuyama indole synthesis is a versatile tin mediated chemical reaction that results in the formation of 2,3-disubstituted indoles. A practical one-pot reaction that can be useful for the creatio… Wikipedia: Category:Name reactions
Fukuyama reduction Reduction The Fukuyama reduction is an organic reaction and an organic reduction in which a thioester is reduced to an aldehyde by a silyl hydride in presence of a catalytic amount of palladium. This reaction w… Wikipedia: Category:Name reactions
FUMARIC ACID Preparation of FUMARIC ACID. Submitted by Nicholas A. Milas. DOI: 10.15227/orgsyn.011.0046. Organic Syntheses
FUMARONITRILE Preparation of FUMARONITRILE. Submitted by David T. Mowry and John Mann Butler1. DOI: 10.15227/orgsyn.030.0046. Organic Syntheses
FUMARYL CHLORIDE Preparation of FUMARYL CHLORIDE. Submitted by L. P. Kyrides. DOI: 10.15227/orgsyn.020.0051. Organic Syntheses
FURAN Preparation of FURAN. Submitted by W. C. Wilson. DOI: 10.15227/orgsyn.007.0040. Organic Syntheses
FURFURAL (2-Furaldehyde) Preparation of 2-Furaldehyde. Submitted by Roger Adams and V. Voorhees. DOI: 10.15227/orgsyn.001.0049. Organic Syntheses
FURFURAL DIACETATE (2-Furanmethanediol, diacetate) Preparation of 2-Furanmethanediol, diacetate. Submitted by R. T. Bertz1. DOI: 10.15227/orgsyn.033.0039. Organic Syntheses
FURYLACRYLIC ACID (2-Furanacrylic acid) Preparation of 2-Furanacrylic acid. Submitted by S. Rajagopalan and P. V. A. Raman. DOI: 10.15227/orgsyn.025.0051. Organic Syntheses
Gabriel–Colman rearrangement Rearrangement The Gabriel–Colman rearrangement is the chemical reaction of a saccharin or phthalimido ester with a strong base, such as an alkoxide, to form substituted isoquinolines. First described in 1900 by che… Wikipedia: Category:Name reactions
Gabriel synthesis The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, the reaction uses potassium phthalimide. The reaction is named after the German c… Wikipedia: Category:Name reactions
GALLACETOPHENONE Preparation of GALLACETOPHENONE. Submitted by I. C. Badhwar and K. Venkataraman. DOI: 10.15227/orgsyn.014.0040. Organic Syntheses
Gallagher–Hollander degradation In the Gallagher–Hollander degradation (1946) pyruvic acid is removed from a linear aliphatic carboxylic acid yielding a new acid with two carbon atoms fewer. The original publication concerns the con… Wikipedia: Category:Name reactions
Ganem oxidation Oxidation In organic chemistry, the Ganem oxidation is a name reaction that allows for the preparation of carbonyls from primary or secondary alkyl halides with the use of trialkylamine N-oxides, such as N-meth… Wikipedia: Category:Name reactions
Gattermann reaction The Gattermann reaction (also known as the Gattermann formylation and the Gattermann salicylaldehyde synthesis) is a chemical reaction in which aromatic compounds are formylated by a mixture of hydro… Wikipedia: Category:Name reactions
GEMINAL ACYLATION-ALKYLATION AT A CARBONYL CENTER USING DIETHYL N-BENZYLIDENEAMINOMETHYLPHOSPHONATE: 2-METHYL-2-PHENYL-4-PENTENAL (4-Pentenal, 2-methyl-2-phenyl-) Preparation of 4-Pentenal, 2-methyl-2-phenyl-. Submitted by Steven K. Davidsen, Gerald W. Phllips, and Stephen F. Martin1. DOI: 10.15227/orgsyn.065.0119. Organic Syntheses
GENERATION AND [2+2] CYCLOADDITIONS OF THIO-SUBSTITUTED KETENES: trans-1-(4-METHOXYPHENYL)-4-PHENYL-3-(PHENYLTHIO)AZETIDIN-2-ONE ((2-Azetidinone, 1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)-, trans-)) Cycloaddition Preparation of (2-Azetidinone, 1-(4-methoxyphenyl)-4-phenyl-3-(phenylthio)-, trans-). Submitted by Rick L. Danheiser, Iwao Okamoto, Michael D. Lawlor, and Thomas W. Lee.1. DOI: 10.15227/orgsyn.080.016… Organic Syntheses
GENERATION AND CYCLIZATION OF 5-HEXENYLLITHIUM: 2-CYCLOPENTYLACETOPHENONE (Ethanone, 2-cyclopentyl-1-phenyl-) Cyclization Preparation of Ethanone, 2-cyclopentyl-1-phenyl-. Submitted by William F. Bailey, Matthew R. Luderer, Michael J. Mealy, and Eric R. Punzalan1. DOI: 10.15227/orgsyn.081.0121. Organic Syntheses
GENERATION AND REACTIONS OF ALKENYLLITHIUM REAGENTS: 2-BUTYLBORNENE Preparation of GENERATION AND REACTIONS OF ALKENYLLITHIUM REAGENTS: 2-BUTYLBORNENE. Submitted by A. Richard Chamberlin, Ellen L. Liotta, and F. Thomas Bond1. DOI: 10.15227/orgsyn.061.0141. Organic Syntheses
GENERATION AND USE OF LITHIUM PENTAFLUOROPROPEN-2-OLATE: 4-HYDROXY-1,1,1,3,3-PENTAFLUORO-2-HEXANONE HYDRATE (2,2,4-Hexanetriol, 1,1,1,3,3-pentafluoro- from 1-Propen-2-ol, 1,1,3,3,3-pentafluoro-, lithium salt) Preparation of 2,2,4-Hexanetriol, 1,1,1,3,3-pentafluoro- from 1-Propen-2-ol, 1,1,3,3,3-pentafluoro-, lithium salt. Submitted by Cheng-Ping Qian, Yu-Zhong Liu, Katsuhiko Tomooka, and Takeshi Nakai1. DO… Organic Syntheses
GENERATION OF 1-PROPYNYLLITHIUM FROM (Z/E)-1-BROMO-1-PROPENE: 6-PHENYLHEX-2-YN-5-EN-4-OL (1-Hexen-4-yn-3-ol, 1-phenyl-, (E)-) Preparation of 1-Hexen-4-yn-3-ol, 1-phenyl-, (E)-. Submitted by Dominique Toussaint and Jean Suffert1. DOI: 10.15227/orgsyn.076.0214. Organic Syntheses
GENERATION OF AN ACETYLENE-TITANIUM ALKOXIDE COMPLEX: PREPARATION OF (Z)-1,2-DIDEUTERIO-1-(TRIMETHYLSILYL)-1-HEXENE ((Silane, (1,2-dideuterio-1-hexenyl)trimethyl-, (Z)-)) Preparation of (Silane, (1,2-dideuterio-1-hexenyl)trimethyl-, (Z)-). Submitted by Hirokazu Urabe, Daisuke Suzuki, and Fumie Sato1. DOI: 10.15227/orgsyn.080.0120. Organic Syntheses
GENERATION OF N,N-DIETHYLCARBAMOYLLITHIUM VIA LITHIUM-TELLURIUM EXCHANGE AND ITS REACTION WITH 3-PHENYLPROPANAL: N,N-DIETHYL-2-HYDROXY-4-PHENYLBUTANAMIDE (Benzenebutanamide, N,N-diethyl-α-hydroxy-) Preparation of Benzenebutanamide, N,N-diethyl-α-hydroxy-. Submitted by Nobuaki Kambe, Toru Inoue, and Noboru Sonoda1. DOI: 10.15227/orgsyn.072.0154. Organic Syntheses
GENERATION OF NONRACEMIC 2-(t-BUTYLDIMETHYLSILYLOXY)-3-BUTYNYLLITHIUM FROM (S)-ETHYL LACTATE: ((S)-4-(t-BUTYLDIMETHYLSILYLOXY)-2-PENTYN-1-OL) Preparation of (S)-4-(t-BUTYLDIMETHYLSILYLOXY)-2-PENTYN-1-OL. Submitted by James A. Marshall, Mathew M. Yanik, Nicholas D. Adams, Keith C. Ellis, and Harry R. Chobanian1. DOI: 10.15227/orgsyn.081.0157… Organic Syntheses
GENERATION OF YNOLATE AND Z-SELECTIVE OLEFINATION OF ACYLSILANES: (Z)-2-METHYL-3-TRIMETHYLSILYL-2-BUTENOIC ACID ((Z)-2-Butenoic acid, 2-methyl-3-trimethylsilyl-) Olefination Preparation of (Z)-2-Butenoic acid, 2-methyl-3-trimethylsilyl-. Submitted by Mitsuru Shindo1, Kenji Matsumoto2, and Kozo Shishido2. DOI: 10.15227/orgsyn.084.0011. Organic Syntheses
GERANYL CHLORIDE (2,6-Octadiene, 1-chloro-3,7-dimethyl-, (E)-) Preparation of 2,6-Octadiene, 1-chloro-3,7-dimethyl-, (E)-. Submitted by Jose G. Calzada and John Hooz1. DOI: 10.15227/orgsyn.054.0063. Organic Syntheses
Gewald reaction The Gewald reaction (or the Gewald aminothiophene synthesis) is an organic reaction involving the condensation of a ketone (or aldehyde when R2 = H) with a α-cyanoester in the presence of elemental su… Wikipedia: Category:Name reactions
Girdler sulfide process The Girdler sulfide (GS) process, also known as the Geib–Spevack (GS) process, is an industrial production method for extracting heavy water (deuterium oxide, D2O) from natural water. Heavy water is … Wikipedia: Category:Name reactions
Glaser coupling Cross-coupling The Glaser coupling is a type of coupling reaction. It is by far one of the oldest coupling reactions and is based on copper compounds like copper(I) chloride or copper(I) bromide and an additional ox… Wikipedia: Category:Name reactions

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