Reactions

1–24 of 3,374

1. Cannizzaro disproportionation: 2 benzaldehyde → benzyl alcohol + sodium benzoateDisproportionationredox Textbook redox disproportionation of an α-H-free aldehyde. Worked example · after Cannizzaro 1853 Scale
2. Claisen-Schmidt aldol: benzaldehyde + acetone → benzalacetoneCondensationC-C bond formation Textbook aldol condensation. Worked example · after Claisen-Schmidt 1881 Scale
3. Diels–Alder cycloaddition: cyclopentadiene + maleic anhydride → endo-norbornene-2,3-dicarboxylic anhydrideCycloaddition[4+2] Textbook [4+2] cycloaddition. Worked example · after Diels-Alder 1928 Scale
4. Friedel-Crafts acylation: benzene + acetyl chloride → acetophenoneElectrophilic aromatic substitution Textbook electrophilic aromatic substitution via the AlCl3-generated acylium ion. Worked example · after Friedel-Crafts 1877 Scale
5. Grignard addition: phenylmagnesium bromide + benzaldehyde → diphenylmethanolOrganometallic addition Textbook Grignard addition. Worked example · after Grignard 1900 Scale
6. Henry reaction (nitroaldol addition)Additionnitroaldol Base-catalysed addition of a nitroalkane to an aldehyde to give a β-nitro alcohol that dehydrates under Knoevenagel-Henry conditions to the conjugated nitroalkene. Worked example · after Henry 1895 Scale
7. Mitsunobu reaction: benzyl alcohol + phthalimide → N-benzyl phthalimideSubstitutiondehydration PPh3/DIAD-mediated dehydrative coupling of an alcohol with an acidic pronucleophile (pKa ≲ 13). Worked example · after Mitsunobu 1967 Scale
8. Suzuki–Miyaura coupling: 4-bromobenzonitrile + phenylboronic acid → 4-cyanobiphenylCross-couplingC-C Canonical Pd(0)-catalysed cross-coupling of an aryl halide with an aryl boronic acid. Worked example · after Suzuki 1979 Scale
9. Williamson ether synthesis: sodium ethoxide + 1-bromobutane → ethyl butyl etherSubstitutionSN2 Textbook SN2 ether-formation. Worked example · after Williamson 1850 Scale
10. Wittig olefination: methyltriphenylphosphonium bromide + benzaldehyde → styreneOlefination Canonical Wittig olefination — the textbook 'make an alkene from an aldehyde' demo. Worked example · after Wittig 1954 Scale
11. Abramov reaction The Abramov reaction is the related conversions of trialkyl to α-hydroxy phosphonates by the addition to carbonyl compounds. Named reaction · Wikipedia
12. Achmatowicz reaction The Achmatowicz reaction, also known as the Achmatowicz rearrangement or the Achmatowicz oxidation, is an organic synthesis in which a furan is converted to a dihydropyran. Named reaction · Wikipedia
13. Adams decarboxylation The Adams decarboxylation is a chemical reaction that involved the decarboxylation of coumarins which have carboxylic acid group in the third position. Named reaction · Wikipedia
14. Adkins–Peterson reaction The Adkins–Peterson reaction is the air oxidation of methanol to formaldehyde with metal oxide catalysts such as iron oxide, molybdenum trioxide or combinations thereof. Named reaction · Wikipedia
15. Akabori amino-acid reaction There are several Akabori amino acid reactions, which are named after Shirō Akabori (Japanese: 赤堀 四郎) (1900–1992), a Japanese chemist. Named reaction · Wikipedia
16. Albright–Goldman oxidationOxidation The Albright–Goldman oxidation is a name reaction of organic chemistry, first described by the American chemists J. Donald Albright and Leon Goldman in 1965. Named reaction · Wikipedia
17. Aldol–Tishchenko reactionCondensation The Aldol–Tishchenko reaction is a tandem reaction involving an aldol reaction and a Tishchenko reaction. Named reaction · Wikipedia
18. Algar–Flynn–Oyamada reaction The Algar–Flynn–Oyamada reaction is a chemical reaction whereby a chalcone undergoes an oxidative cyclization to form a flavonol. Named reaction · Wikipedia
19. Allan–Robinson reactionCyclization The Allan–Robinson reaction is the chemical reaction of o-hydroxyaryl ketones with aromatic anhydrides to form flavones (or isoflavones). Named reaction · Wikipedia
20. Allen–Millar–Trippett rearrangementRearrangement The Allen–Millar–Trippett rearrangement is a ring expansion reaction in which a cyclic phosphine is transformed into a cyclic phosphine oxide. Named reaction · Wikipedia
21. Amadori rearrangementRearrangement The Amadori rearrangement is an organic reaction describing the acid or base catalyzed isomerization or rearrangement reaction of the N-glycoside of an aldose or the glycosylamine to the corresponding 1-amino-1-deoxy-ketose. Named reaction · Wikipedia
22. Andrussow process The Andrussow process is the dominant industrial process for the production of hydrogen cyanide. Named reaction · Wikipedia
23. Angeli–Rimini reaction The Angeli–Rimini reaction is an organic reaction between an aldehyde and N-hydroxybenzenesulfonamide in presence of base forming a hydroxamic acid. Named reaction · Wikipedia
24. Appel reactionSubstitution The Appel reaction is an organic reaction that converts an alcohol into an alkyl chloride using triphenylphosphine and carbon tetrachloride. Named reaction · Wikipedia