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88 reactions imported from Wikipedia named-reactions and Organic Syntheses archives. Filter by source or search by name + summary.

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Equation Name Summary Source
LITHIUM AMIDES AS HOMOCHIRAL AMMONIA EQUIVALENTS FOR CONJUGATE ADDITIONS TO α,β-UNSATURATED ESTERS: ASYMMETRIC SYNTHESIS OF (S)-β-LEUCINE Addition Preparation of LITHIUM AMIDES AS HOMOCHIRAL AMMONIA EQUIVALENTS FOR CONJUGATE ADDITIONS TO α,β-UNSATURATED ESTERS: ASYMMETRIC SYNTHESIS OF (S)-β-LEUCINE. Submitted by Stephen G. Davies1, Ai M. Fletche… Organic Syntheses
Lumière–Barbier method Organometallic addition The Lumière–Barbier method is a method of acetylating aromatic amines in aqueous solutions. Illustrative is the acetylation of aniline. First aniline is dissolved in water using one equivalent of hyd… Wikipedia: Category:Name reactions
MANGANESE-COPPER-CATALYZED CONJUGATE ADDITION OF ORGANOMAGNESIUM REAGENTS TO α,β-ETHYLENIC KETONES: 2-(1,1-DIMETHYLPENTYL)-5-METHYL-CYCLOHEXANONE FROM PULEGONE (Cyclohexanone, 2-(1,1-dimethylpentyl)-5-methyl-) Addition Preparation of Cyclohexanone, 2-(1,1-dimethylpentyl)-5-methyl-. Submitted by S. Marquais, M. Alami, and G. Cahiez1. DOI: 10.15227/orgsyn.072.0135. Organic Syntheses
Mannich reaction Addition In organic chemistry, the Mannich reaction is a three-component organic reaction that involves the amino alkylation of the α-position of a ketone or aldehyde with an aldehyde and a nullary, primary, o… Wikipedia: Category:Name reactions
Michael addition reaction Addition In organic chemistry, the Michael reaction or Michael 1,4 addition is a reaction between a Michael donor (an enolate or other nucleophile) and a Michael acceptor (usually an α,β-unsaturated carbonyl) … Wikipedia: Category:Name reactions
Michaelis–Arbuzov reaction Addition The Michaelis–Arbuzov reaction (also called the Arbuzov reaction) is the chemical reaction of a trivalent phosphorus ester with an alkyl halide to form a pentavalent phosphorus species and another alk… Wikipedia: Category:Name reactions
Michaelis–Becker reaction Addition The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate. Yi… Wikipedia: Category:Name reactions
NICKEL-CATALYZED COUPLING OF ARYL O-CARBAMATES WITH GRIGNARD REAGENTS: 2,7-DIMETHYLNAPHTHALENE (Naphthalene, 2,7-dimethyl-) Organometallic addition Preparation of Naphthalene, 2,7-dimethyl-. Submitted by Carol Dallaire1a , Isabelle Kolber 1b , and Marc Gingras 1c. DOI: 10.15227/orgsyn.078.0042. Organic Syntheses
Nitro-Mannich reaction Addition The nitro-Mannich reaction (or aza-Henry reaction) is the nucleophilic addition of a nitroalkane (or the corresponding nitronate anion) to an imine, resulting in the formation of a beta-nitroamine. Wi… Wikipedia: Category:Name reactions
NITRONES FOR INTRAMOLECULAR 1,3-DIPOLAR CYCLOADDITIONS: HEXAHYDRO-1,3,3,6-TETRAMETHYL-2,1-BENZISOXAZOLINE (2,1-Benzisoxazole, 1,3,3a,4,5,6,7,7a-octahydro-1,3,3,6-tetramethyl-) Cycloaddition Preparation of 2,1-Benzisoxazole, 1,3,3a,4,5,6,7,7a-octahydro-1,3,3,6-tetramethyl-. Submitted by Norman A. LeBel and Dorothy Hwang1. DOI: 10.15227/orgsyn.058.0106. Organic Syntheses
NUCLEOPHILIC HYDROXYMETHYLATION BY THE (ISOPROPOXYDIMETHYLSILYL)METHYL GRIGNARD REAGENT: 1-(HYDROXYMETHYL)CYCLOHEXANOL FROM CYCLOHEXANONE (Cyclohexanemethanol, 1-hydroxy-) Organometallic addition Preparation of Cyclohexanemethanol, 1-hydroxy-. Submitted by Kohei Tamao, Neyoshi Ishida, Yoshihiko Ito, and Makoto Kumada1. DOI: 10.15227/orgsyn.069.0096. Organic Syntheses
PALLADIUM(0)-CATALYZED syn-1,4-ADDITION OF CARBOXYLIC ACIDS TO CYCLOPENTADIENE MONOEPOXIDE: cis-3-ACETOXY-5-HYDROXYCYCLOPENT-1-ENE (4-Cyclopentene-1,3-diol, monoacetate, cis-) Addition Preparation of 4-Cyclopentene-1,3-diol, monoacetate, cis-. Submitted by Donald R. Deardorff and David C. Myles1. DOI: 10.15227/orgsyn.067.0114. Organic Syntheses
Palladium-catalyzed 1,4-Addition of Terminal Alkynes to Conjugated Enones Addition Preparation of Palladium-catalyzed 1,4-Addition of Terminal Alkynes to Conjugated Enones. Submitted by Feng Zhou, Liang Chen and Chao-Jun Li1*. DOI: 10.15227/orgsyn.091.0072. Organic Syntheses
PHOSPHINE–NICKEL COMPLEX CATALYZED CROSS-COUPLING OF GRIGNARD REAGENTS WITH ARYL AND ALKENYL HALIDES: 1,2-DIBUTYLBENZENE (Benzene, 1,2-di-n-butyl-) Organometallic addition Preparation of Benzene, 1,2-di-n-butyl-. Submitted by Makoto Kumada, Kohei Tamao, and Koji Sumitani1. DOI: 10.15227/orgsyn.058.0127. Organic Syntheses
PHOTOINDUCED-ADDITION OF METHANOL TO (5S)-(5-O-tert-BUTYLDIMETHYLSILOXYMETHYL)FURAN-2(5H)-ONE: (4R,5S)-4-HYDROXYMETHYL-(5-O-tert-BUTYLDIMETHYLSILOXYMETHYL)FURAN-2(5H)-ONE (2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (S)- and D-erythro-Pentonic acid, 2,3-dideoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-3-(hydroxymethyl)-, γ-lactone) Addition Preparation of 2(5H)-Furanone, 5-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, (S)- and D-erythro-Pentonic acid, 2,3-dideoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-3-(hydroxymethyl)-, γ-lactone. S… Organic Syntheses
PREPARATION AND [2+2] CYCLOADDITION OF 1-TRIISOPROPYLSILOXY-1-HEXYNE WITH METHYL CROTONATE: 3-BUTYL-4-METHYL-2-TRIISOPROPYLSILOXY-CYCLOBUT-2-ENECARBOXYLIC ACID METHYL ESTER Cycloaddition Preparation of PREPARATION AND [2+2] CYCLOADDITION OF 1-TRIISOPROPYLSILOXY-1-HEXYNE WITH METHYL CROTONATE: 3-BUTYL-4-METHYL-2-TRIISOPROPYLSILOXY-CYCLOBUT-2-ENECARBOXYLIC ACID METHYL ESTER. Submitted b… Organic Syntheses
PREPARATION AND THREE-CARBON + TWO-CARBON CYCLOADDITION OF CYCLOPROPENONE 1,3-PROPANEDIOL KETAL: 5,5-DICYANO-4-PHENYL-2-CYCLOPENTEN-1-ONE 1,3-PROPANEDIOL KETAL (4,8-Dioxaspiro[2.5]oct-1-ene and 6,10-Dioxaspiro[4.5]dec-3-ene-1,1-dicarbonitrile, 2-phenyl-) Cycloaddition Preparation of 4,8-Dioxaspiro[2.5]oct-1-ene and 6,10-Dioxaspiro[4.5]dec-3-ene-1,1-dicarbonitrile, 2-phenyl-. Submitted by Dale L. Boger, Christine E. Brotherton, and Gunda I. Georg1. DOI: 10.15227/org… Organic Syntheses
Preparation of 1,5-Disubstituted 1,2,3-Triazoles via Ruthenium-catalyzed Azide Alkyne Cycloaddition Cycloaddition Preparation of Preparation of 1,5-Disubstituted 1,2,3-Triazoles via Ruthenium-catalyzed Azide Alkyne Cycloaddition. Submitted by James S. Oakdale and Valery V. Fokin1. DOI: 10.15227/orgsyn.090.0096. Organic Syntheses
PREPARATION OF ENANTIOMERICALLY ENRICHED (1S)-1-PHENYLPROPAN-1-AMINE HYDROCHLORIDE BY A CATALYTIC ADDITION OF DIORGANOZINC REAGENTS TO IMINES (Benzenemethanamine, α-ethyl-, hydrochloride, (αS)-) Addition Preparation of Benzenemethanamine, α-ethyl-, hydrochloride, (αS)-. Submitted by Jean-Nicolas Desrosiers, Alexandre Côté, Alessandro A. Boezio, and André B. Charette1. DOI: 10.15227/orgsyn.083.0005. Organic Syntheses
PREPARATION OF POLYQUINANES BY DOUBLE ADDITION OF VINYL ANIONS TO SQUARATE ESTERS: 4,5,6,6a-TETRAHYDRO-3a-HYDROXY-2,3-DIISOPROPOXY-4,6a-DIMETHYL-1(3aH)-PENTALENONE Addition Preparation of PREPARATION OF POLYQUINANES BY DOUBLE ADDITION OF VINYL ANIONS TO SQUARATE ESTERS: 4,5,6,6a-TETRAHYDRO-3a-HYDROXY-2,3-DIISOPROPOXY-4,6a-DIMETHYL-1(3aH)-PENTALENONE. Submitted by Tina Mo… Organic Syntheses
PREPARATION OF SUBSTITUTED PYRIDINES VIA REGIOCONTROLLED [4 + 2] CYCLOADDITIONS OF OXIMINOSULFONATES: METHYL 5-METHYLPYRIDINE-2-CARBOXYLATE ((2-Pyridinecarboxylic acid, 5-methyl-, methyl ester)) Cycloaddition Preparation of (2-Pyridinecarboxylic acid, 5-methyl-, methyl ester). Submitted by Rick L. Danheiser, Adam R. Renslo, David T. Amos, and Graham T. Wright.1. DOI: 10.15227/orgsyn.080.0133. Organic Syntheses
Reformatsky reaction Organometallic addition The Reformatsky reaction (sometimes transliterated as Reformatskii reaction) is an organic reaction which condenses aldehydes or ketones with α-halo esters using metallic zinc to form β-hydroxy-esters… Wikipedia: Category:Name reactions
REGIOSELECTIVE MANNICH CONDENSATION WITH DIMETHYL(METHYLENE)AMMONIUM TRIFLUOROACETATE: 1-(DIMETHYLAMINO)-4-METHYL-3-PENTANONE (3-Pentanone, 1-(dimethylamino)-4-methyl-) Addition Preparation of 3-Pentanone, 1-(dimethylamino)-4-methyl-. Submitted by Michel Gaudry1, Yves Jasor, and Trung Bui Khac. DOI: 10.15227/orgsyn.059.0153. Organic Syntheses
RHODIUM-CATALYZED ENANTIOSELECTIVE ADDITION OF ARYLBORONIC ACIDS TO IN SITU GENERATED N-BOC ARYLIMINES. PREPARATION OF (S)-TERT-BUTYL (4-CHLOROPHENYL)(THIOPHEN-2-YL)METHYLCARBAMATE Addition Preparation of RHODIUM-CATALYZED ENANTIOSELECTIVE ADDITION OF ARYLBORONIC ACIDS TO IN SITU GENERATED N-BOC ARYLIMINES. PREPARATION OF (S)-TERT-BUTYL (4-CHLOROPHENYL)(THIOPHEN-2-YL)METHYLCARBAMATE. Sub… Organic Syntheses
RHODIUM-CATALYZED HETEROCYCLOADDITION OF A DIAZOMALONATE AND A NITRILE: 4-CARBOMETHOXY-5-METHOXY-2-PHENYL-1,3-OXAZOLE (4-Oxazolecarboxylic acid, 5-methoxy-2-phenyl-, methyl ester) Cycloaddition Preparation of 4-Oxazolecarboxylic acid, 5-methoxy-2-phenyl-, methyl ester. Submitted by Joshua S. Tullis and Paul Helquist1. DOI: 10.15227/orgsyn.074.0229. Organic Syntheses
SELECTIVE HYDROBORATION OF A 1,3,7-TRIENE: HOMOGERANIOL (3,7-Nonadien-1-ol, 4,8-dimethyl-, (E)-) Addition Preparation of 3,7-Nonadien-1-ol, 4,8-dimethyl-, (E)-. Submitted by Eric J. Leopold1. DOI: 10.15227/orgsyn.064.0164. Organic Syntheses
STEREOSELECTIVE NICKEL-CATALYZED 1,4-HYDROBORATION OF 1,3-DIENES ((Z)-Dec-2-en-1-ol) Addition Preparation of (Z)-Dec-2-en-1-ol. Submitted by Robert J. Ely and James P. Morken1. DOI: 10.15227/orgsyn.088.0342. Organic Syntheses
SYNTHESIS AND [3+2] CYCLOADDITION OF A 1,1-DIALKOXY-2-METHYLENECYCLOPROPANE: 6,6-DIMETHYL-1-METHYLENE-4,8-DIOXASPIRO[2.5]OCTANE and cis-5-(5,5-DIMETHYL-1,3-DIOXAN-2-YLIDENE)HEXAHYDRO-1(2H)-PENTALEN-2-ONE ((4,8-Dioxaspiro[2.5]octane, 6,6-dimethyl-1-methylene-)) Cycloaddition Preparation of (4,8-Dioxaspiro[2.5]octane, 6,6-dimethyl-1-methylene-). Submitted by Masaharu Nakamura1, Xiao Qun Wang1, Masahiko Isaka1, Shigeru Yamago2, and Eiichi Nakamura1. DOI: 10.15227/orgsyn.080… Organic Syntheses
SYNTHESIS AND UTILIZATION OF INDIUM (I) IODIDE FOR IN SITU FORMATION OF ENANTIOENRICHED ALLENYLINDIUM REAGENTS AND THEIR ADDITION TO ALDEHYDES: (2R,3S,4S)-1-(tert-BUTYLDIPHENYLSILYLOXY)-2,4-DIMETHYL-5-HEXYN-3-OL (5-Hexyn-3-ol, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2,4-dimethyl-, (2R,3S,4S)-) Addition Preparation of 5-Hexyn-3-ol, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2,4-dimethyl-, (2R,3S,4S)-. Submitted by Brian A. Johns, Charsetta M. Grant, and James A. Marshall1. DOI: 10.15227/orgsyn.079.005… Organic Syntheses
SYNTHESIS OF 2α-BENZYLOXY-8-OXABICYCLO[3.2.1]OCT-6-EN-3-ONE BY [4 + 3] CYCLOADDITION Cycloaddition Preparation of SYNTHESIS OF 2α-BENZYLOXY-8-OXABICYCLO[3.2.1]OCT-6-EN-3-ONE BY [4 + 3] CYCLOADDITION. Submitted by María Vidal-Pascual, Carolina Martínez-Lamenca, and H. M. R. Hoffmann1. DOI: 10.15227/… Organic Syntheses
SYNTHESIS OF A KEY β-LACTAM INTERMEDIATE BY A [2 + 2] CYCLOADDITION ROUTE: 4-ACETOXYAZETIDIN-2-ONE (2-Azetidinone, 4-(acetyloxy)-) Cycloaddition Preparation of 2-Azetidinone, 4-(acetyloxy)-. Submitted by Stuart J. Mickel1, Shi-Nung Hsiao, and Marvin J. Miller2. DOI: 10.15227/orgsyn.065.0135. Organic Syntheses
SYNTHESIS OF SUBSTITUTED INDAZOLES VIA [3+2] CYCLOADDITION OF BENZYNE AND DIAZO COMPOUNDS (1H-indazole-3-carboxylic acid, ethyl ester) Cycloaddition Preparation of 1H-indazole-3-carboxylic acid, ethyl ester. Submitted by Feng Shi and Richard C. Larock1. DOI: 10.15227/orgsyn.087.0095. Organic Syntheses
SYNTHESIS OF TERT-BUTYL (1S,2S)-2-METHYL-3-OXO-1-PHENYLPROPYLCARBAMATE BY ASYMMETRIC MANNICH REACTION Addition Preparation of SYNTHESIS OF TERT-BUTYL (1S,2S)-2-METHYL-3-OXO-1-PHENYLPROPYLCARBAMATE BY ASYMMETRIC MANNICH REACTION. Submitted by Jung Woon Yang, Subhas Chandra Pan, and Benjamin List1. DOI: 10.15227… Organic Syntheses
TANDEM NUCLEOPHILIC ADDITION / FRAGMENTATION OF VINYLOGOUS ACYL TRIFLATES: 2-METHYL-2-(1-OXO-5-HEPTYNYL)-1,3-DITHIANE Addition Preparation of TANDEM NUCLEOPHILIC ADDITION / FRAGMENTATION OF VINYLOGOUS ACYL TRIFLATES: 2-METHYL-2-(1-OXO-5-HEPTYNYL)-1,3-DITHIANE. Submitted by Marilda P. Lisboa, Tung T. Hoang, and Gregory B. Dudl… Organic Syntheses
THE PREPARATION OF CYCLOHEPT-4-ENONES BY RHODIUM-CATALYZED INTERMOLECULAR [5+2] CYCLOADDITION Cycloaddition Preparation of THE PREPARATION OF CYCLOHEPT-4-ENONES BY RHODIUM-CATALYZED INTERMOLECULAR [5+2] CYCLOADDITION. Submitted by Paul A. Wender1 , Adam B. Lesser1 , , and Lauren E. Sirois1. DOI: 10.15227/or… Organic Syntheses
TITANIUM-MEDIATED ADDITION OF SILYL DIENOL ETHERS TO ELECTROPHILIC GLYCINE: 4-KETOPIPECOLIC ACID HYDROCHLORIDE (Pipecolic acid, 4-oxo-, hydrochloride) Addition Preparation of Pipecolic acid, 4-oxo-, hydrochloride. Submitted by Clarisse Mühlemann, Peter Hartmann, and Jean-Pierre Obrecht1. DOI: 10.15227/orgsyn.071.0200. Organic Syntheses
TRIFLUOROMETHANESULFONIMIDE-CATALYZED (2 + 2)-CYCLOADDITION OF SILYL ENOL ETHERS WITH α,β-UNSATURATED ESTERS: 1-(tert-BUTYLDIMETHYLSILOXY)-8-(METHOXYCARBONYL)-6-METHYLBICYCLO[4.2.0]OCTANE Cycloaddition Preparation of TRIFLUOROMETHANESULFONIMIDE-CATALYZED (2 + 2)-CYCLOADDITION OF SILYL ENOL ETHERS WITH α,β-UNSATURATED ESTERS: 1-(tert-BUTYLDIMETHYLSILOXY)-8-(METHOXYCARBONYL)-6-METHYLBICYCLO[4.2.0]OCTA… Organic Syntheses
USE OFCERIUM(III) CHLORIDE IN THE REACTIONS OF CARBONYL COMPOUNDS WITH ORGANOLITHIUMS OR GRIGNARD REAGENTS FOR THE SUPPRESSION OF ABNORMAL REACTIONS:1-BUTYL-1,2,3,4-TETRAHYDRO-1-NAPHTHOL Organometallic addition Preparation of USE OFCERIUM(III) CHLORIDE IN THE REACTIONS OF CARBONYL COMPOUNDS WITH ORGANOLITHIUMS OR GRIGNARD REAGENTS FOR THE SUPPRESSION OF ABNORMAL REACTIONS:1-BUTYL-1,2,3,4-TETRAHYDRO-1-NAPHTHO… Organic Syntheses

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