Addition reactions
3,374 reactions: 10 worked examples with a reagent table you can scale, 503 named reactions and 2,861 checked procedures from Organic Syntheses.
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- 1,2-Addition of a functionalized zinc-copper organometallic [RCu(CN)ZnI] to an α,β-unsaturated aldehyde: (E)-2-(4-hydroxy-6-phenyl-5-hexenyl)-1H-isoindole-1,3(2H)-dioneAddition
- Addition of an ethylcopper complex to 1-octyne: (E)-5-ethyl-1,4-undecadieneAddition
- Addition of dialkylamines to myrcene: N,N-diethylgeranylamineAddition
- Addition of organolithium reagents to allyl alcohol: 2-methyl-1-hexanolAddition
- Aprotic double Michael addition: 1,3-dimethyl-5-oxobicyclo[2.2.2]octane-2-carboxylic acidAddition
- Asymmetric hydroboration of 5-substituted cyclopentadienes: synthesis of methyl (1 R,5R)-5-hydroxy-2-cyclopentene-1-acetateAddition
- Benzyl isopropoxymethyl carbamate - an aminomethylating reagent for Mannich reactions of titanium enolatesAddition
- Catalytic asymmetric addition of an in-situ prepared arylzinc to cyclohexanecarboxaldehyde: (R)-(+)-α-cyclohexyl-3-methoxy-benzenemethanolAddition
- Catalytic enantioselective addition of dialkylzincs to aldehydes using (2S)-(−)-3-exo-(dimethylamino)isoborneol [(2S)-DAIB]: (S)-1-phenyl-1-propanolAddition
- Catalytic enantioselective addition of terminal alkynes to aldehydes: preparation of (S)-(-)-1,3-diphenyl-2-propyn-1-ol and (S)-(-)-4-methyl-1-phenyl-2-pentyn-1,4-diolAddition
- Conjugate addition of a vinylzirconium reagent: 3-(1-octen-1-yl)cyclopentanoneAddition
- Copper-catalyzed conjugate addition of a zinc homoenolate: ethyl 3-[3-(trimethylsilyloxy)cyclohex-2-enyl]propionateAddition
- Copper-catalyzed conjugate addition of functionalized organozinc reagents to α,β-unsaturated ketones: ethyl 5-(3-oxocyclohexyl)pentanoateAddition
- Copper(I) iodide dimethyl sulfide catalyzed addition of a vinylzirconium reagent (preparation of 4-phenyl-5(E)-decen-2-one)Addition
- Cyanide-catalyzed conjugate addition of aryl aldehydes: 4-oxo-4-(3-pyridyl)butyronitrileAddition
- Diels-Alder addition of perchlorobenzyne: benzobarreleneAddition
- Diethylaminotrimethylsilane-catalyzed 1,4-addition of aldehydes to vinyl ketones: (3R)-3,7-dimethyl-2-(3-oxobutyl)-6-octenalAddition
- Enantioselective addition of butyllithium in the presence of the chiral cosolvent DDB: (R)-(+)-1-phenyl-1-pentanolAddition
- Highly efficient addition of activated methylene compounds to alkenes catalyzed by gold and silverAddition
- Highly reactive calcium for the preparation of organocalcium reagents: 1-adamantyl calcium halides and their addition to ketones: 1-(1-adamantyl)cyclohexanolAddition
- Homoconjugate addition of nucleophiles to cyclopropane-1,1-dicarboxylate derivatives: 2-oxo-1-phenyl-3-pyrrolidinecarboxylic acidAddition
- Lithium amides as homochiral ammonia equivalents for conjugate additions to α,β-unsaturated esters: asymmetric synthesis of (S)-β-leucineAddition
- Manganese-copper-catalyzed conjugate addition of organomagnesium reagents to α,β-ethylenic ketones: 2-(1,1-dimethylpentyl)-5-methyl-cyclohexanone from pulegoneAddition
- 3'-Nitro-1-phenylethanol by addition of methyltriisopropoxytitanium to m-nitrobenzaldehydeAddition
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