1,2-Addition of a functionalized zinc-copper organometallic [RCu(CN)ZnI] to an α,β-unsaturated aldehyde: (E)-2-(4-hydroxy-6-phenyl-5-hexenyl)-1H-isoindole-1,3(2H)-dione
CAS index name: 1H-Isoindole-1,3(2H)-dione, 2-(4-hydroxy-6-phenyl-5-hexenyl)-
Organic SynthesesAddition
![Reaction scheme of 1,2-Addition of a functionalized zinc-copper organometallic [RCu(CN)ZnI] to an α,β-unsaturated aldehyde: (E)-2-(4-hydroxy-6-phenyl-5-hexenyl)-1H-isoindole-1,3(2H)-dione from Organic Syntheses](/orgsyn-image/CV9P0502.gif)
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
The compound this preparation makes is not in the catalogue, so no reagents or figures are listed here.
More addition reactions
- Addition of an ethylcopper complex to 1-octyne: (E)-5-ethyl-1,4-undecadiene
- Addition of dialkylamines to myrcene: N,N-diethylgeranylamine
- Addition of organolithium reagents to allyl alcohol: 2-methyl-1-hexanol
- Aprotic double Michael addition: 1,3-dimethyl-5-oxobicyclo[2.2.2]octane-2-carboxylic acid
- Asymmetric hydroboration of 5-substituted cyclopentadienes: synthesis of methyl (1 R,5R)-5-hydroxy-2-cyclopentene-1-acetate
- Benzyl isopropoxymethyl carbamate - an aminomethylating reagent for Mannich reactions of titanium enolates