Synthesis of indoles by palladium-catalyzed reductive N-heteroannulation of 2-nitrostyrenes: methyl indole-4-carboxylate
CAS index name: (1H-Indole-4-carboxylic acid, methyl ester)
Organic SynthesesCyclization
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
| Compound | Role | Equiv | MW (g/mol) | ρ (g/mL) | Safety |
|---|---|---|---|---|---|
| Methyl 1H-indole-4-carboxylate39830-66-5 · C10H9NO2 | product | — | 175.19 | — | Warning |
More cyclization reactions
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- [3 + 4] Annulation using a [β-(trimethylsilyl)acryloyl]silane and the lithium enolate of an α,β-unsaturated methyl ketone: (1R,6S,7S)-4-(tert-butyldimethylsiloxy)-6-(trimethylsilyl)bicyclo[5.4.0]undec-4-en-2-one
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