Acyloin condensation by thiazolium ion catalysis: butyroin
CAS index name: 4-Octanone, 5-hydroxy-
Organic SynthesesCondensation
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
| Compound | Role | Equiv | MW (g/mol) | ρ (g/mL) | Safety |
|---|---|---|---|---|---|
| 5-Hydroxy-4-octanone496-77-5 · C8H16O2 | product | — | 144.21 | — | Not classified |
More condensation reactions
- Acyloin condensation in which chlorotrimethylsilane is used as a trapping agent: 1,2-bis(trimethylsilyloxy)cyclobutene and 2-hydroxycyclobutanone
- Amide formation by decarboxylative condensation of hydroxylamines and α-ketoacids: N-[(1S)-1 phenylethyl]-benzeneacetamide
- Catalytic asymmetric acyl halide-aldehyde cyclocondensation reaction
- Catalytic asymmetric synthesis of nitroaldols using a lanthanum-lithium-BINOL complex: (2S,3S)-2-nitro-5-phenyl-1,3-pentanediol
- Condensation of (−)-dimenthyl succinate dianion with 1,ω-dihalides: (+)-(1S,2S)-cyclopropane-1,2-dicarboxylic acid
- Condensation of dimethyl 1,3-acetonedicarboxylate with 1,2-dicarbonyl compounds: cis-bicyclo[3.3.0]octane-3,7-diones