Addition reactions
3,374 reactions: 10 worked examples with a reagent table you can scale, 503 named reactions and 2,861 checked procedures from Organic Syntheses.
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- Kharasch additionAddition The Kharasch addition is an organic reaction and a metal-catalysed free radical addition of CXCl3 compounds (X = Cl, Br, H) to alkenes.
- Mannich reactionAddition In organic chemistry, the Mannich reaction is a three-component organic reaction that involves the amino alkylation of the α-position of a ketone or aldehyde with an aldehyde and a nullary, primary, or secondary amine (−NH2).
- Michael addition reactionAddition In organic chemistry, the Michael reaction or Michael 1,4 addition is a reaction between a Michael donor (an enolate or other nucleophile) and a Michael acceptor (usually an α,β-unsaturated carbonyl) to produce a Michael adduct by creating a carbon-carbon bond at the acceptor's β-carbon.
- Michaelis–Arbuzov reactionAddition The Michaelis–Arbuzov reaction (also called the Arbuzov reaction) is the chemical reaction of a trivalent phosphorus ester with an alkyl halide to form a pentavalent phosphorus species and another alkyl halide.
- Michaelis–Becker reactionAddition The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate.
- Nitro-Mannich reactionAddition The nitro-Mannich reaction (or aza-Henry reaction) is the nucleophilic addition of a nitroalkane (or the corresponding nitronate anion) to an imine, resulting in the formation of a beta-nitroamine.