chempirical
Reaction database

Addition reactions

3,374 reactions: 10 worked examples with a reagent table you can scale, 503 named reactions and 2,861 checked procedures from Organic Syntheses.

25–46 of 46

  1. Enantioselective addition of butyllithium in the presence of the chiral cosolvent DDB: (R)-(+)-1-phenyl-1-pentanolAddition Org. Synth. Coll. Vol. 7, p. 447; Vol. 61, p. 42 · Seebach and Hidber
  2. Highly efficient addition of activated methylene compounds to alkenes catalyzed by gold and silverAddition Org. Synth. Vol. 84, p. 222 · Li and Yao
  3. Highly reactive calcium for the preparation of organocalcium reagents: 1-adamantyl calcium halides and their addition to ketones: 1-(1-adamantyl)cyclohexanolAddition Org. Synth. Coll. Vol. 9, p. 9; Vol. 72, p. 147 · Rieke et al.
  4. Homoconjugate addition of nucleophiles to cyclopropane-1,1-dicarboxylate derivatives: 2-oxo-1-phenyl-3-pyrrolidinecarboxylic acidAddition Org. Synth. Coll. Vol. 7, p. 411; Vol. 60, p. 66 · Singh and Danishefsky
  5. Lithium amides as homochiral ammonia equivalents for conjugate additions to α,β-unsaturated esters: asymmetric synthesis of (S)-β-leucineAddition Org. Synth. Vol. 87, p. 143 · Davies et al.
  6. Manganese-copper-catalyzed conjugate addition of organomagnesium reagents to α,β-ethylenic ketones: 2-(1,1-dimethylpentyl)-5-methyl-cyclohexanone from pulegoneAddition Org. Synth. Coll. Vol. 9, p. 328; Vol. 72, p. 135 · Marquais et al.
  7. 3'-Nitro-1-phenylethanol by addition of methyltriisopropoxytitanium to m-nitrobenzaldehydeAddition Org. Synth. Coll. Vol. 8, p. 495; Vol. 67, p. 180 · Imwinkelried and Seebach
  8. Palladium-catalyzed 1,4-Addition of Terminal Alkynes to Conjugated EnonesAddition Org. Synth. Vol. 91, p. 72 · Zhou et al.
  9. Palladium(0)-catalyzed syn-1,4-addition of carboxylic acids to cyclopentadiene monoepoxide: cis-3-acetoxy-5-hydroxycyclopent-1-eneAddition Org. Synth. Coll. Vol. 8, p. 13; Vol. 67, p. 114 · Deardorff and Myles
  10. Photoinduced-addition of methanol to (5S)-(5-O-tert-butyldimethylsiloxymethyl)furan-2(5H)-one: (4R,5S)-4-hydroxymethyl-(5-O-tert-butyldimethylsiloxymethyl)furan-2(5H)-oneAddition Org. Synth. Vol. 75, p. 139 · Mann and Weymouth-Wilson
  11. Preparation of enantiomerically enriched (1S)-1-phenylpropan-1-amine hydrochloride by a catalytic addition of diorganozinc reagents to iminesAddition Org. Synth. Vol. 83, p. 5 · Desrosiers et al.
  12. Preparation of polyquinanes by double addition of vinyl anions to squarate esters: 4,5,6,6a-tetrahydro-3a-hydroxy-2,3-diisopropoxy-4,6a-dimethyl-1(3aH)-pentalenoneAddition Org. Synth. Coll. Vol. 9, p. 670; Vol. 74, p. 169 · Morwick and Paquette
  13. Regioselective Mannich condensation with dimethyl(methylene)ammonium trifluoroacetate: 1-(dimethylamino)-4-methyl-3-pentanoneAddition Org. Synth. Coll. Vol. 6, p. 474; Vol. 59, p. 153 · Gaudry et al.
  14. Rhodium-catalyzed enantioselective addition of arylboronic acids to in situ generated N-BOC arylimines. Preparation of (S)-tert-butyl (4-chlorophenyl)(thiophen-2-yl)methylcarbamateAddition Org. Synth. Vol. 86, p. 360 · Storgaard and Ellman
  15. Selective hydroboration of a 1,3,7-triene: homogeraniolAddition Org. Synth. Coll. Vol. 7, p. 258; Vol. 64, p. 164 · Leopold
  16. Stereoselective nickel-catalyzed 1,4-hydroboration of 1,3-dienesAddition Org. Synth. Vol. 88, p. 342 · Ely and Morken
  17. Synthesis and utilization of indium (I) iodide for in situ formation of enantioenriched allenylindium reagents and their addition to aldehydes: (2R,3S,4S)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-5-hexyn-3-olAddition Org. Synth. Vol. 79, p. 59 · Johns et al.
  18. Synthesis of tert-butyl (1S,2S)-2-methyl-3-oxo-1-phenylpropylcarbamate by asymmetric Mannich reactionAddition Org. Synth. Vol. 86, p. 11 · Yang et al.
  19. Tandem nucleophilic addition / fragmentation of vinylogous acyl triflates: 2-methyl-2-(1-oxo-5-heptynyl)-1,3-dithianeAddition Org. Synth. Vol. 88, p. 353 · Lisboa et al.
  20. Titanium-mediated addition of silyl dienol ethers to electrophilic glycine: 4-ketopipecolic acid hydrochlorideAddition Org. Synth. Coll. Vol. 9, p. 526; Vol. 71, p. 200 · Mühlemann et al.
  21. 3-Trimethylsilyl-3-buten-2-one as Michael acceptor for conjugate addition-annelation: cis-4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-2(3H)-naphthalenoneAddition Org. Synth. Coll. Vol. 6, p. 666; Vol. 58, p. 158 · Boeckman et al.
  22. 3-Trimethylsilyl-3-buten-2-one: a Michael acceptorAddition Org. Synth. Coll. Vol. 6, p. 1033; Vol. 58, p. 152 · Boeckman et al.