chempirical
Reaction database

Cyclization reactions

3,374 reactions: 10 worked examples with a reagent table you can scale, 503 named reactions and 2,861 checked procedures from Organic Syntheses.

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  1. Preparation of 5-Hydroxycyclopentenones Via Conjugate Addition-Initiated Nazarov CyclizationCyclization Org. Synth. Vol. 91, p. 93 · Brooks et al.
  2. Preparation of Tetrahydroisoquinoline-3-ones Via Cyclization of Phenyl Acetamides Using Eaton's ReagentCyclization Org. Synth. Vol. 89, p. 44 · Yang et al.
  3. Reductive annulation of vinyl sulfones: bicyclo[4.3.0.]non-1-en-4-oneCyclization Org. Synth. Coll. Vol. 8, p. 38; Vol. 67, p. 163 · Lin and Paquette
  4. Synthesis of 2,3-disubstituted indoles via palladium-catalyzed annulation of internal alk ynes: 3-methyl-2-(trimethylsilyl)indoleCyclization Org. Synth. Vol. 88, p. 377 · Chen et al.
  5. Synthesis of Et2SBr•SbCl5Br and its use in biomimetic brominative polyene cyclizationsCyclization Org. Synth. Vol. 88, p. 54 · Snyder and Treitler
  6. Synthesis of indoles by palladium-catalyzed reductive N-heteroannulation of 2-nitrostyrenes: methyl indole-4-carboxylateCyclization Org. Synth. Vol. 80, p. 75 · Söderberg et al.
  7. Synthesis of Quinolines by Electrophilic Cyclization of N-(2-Alkynyl)Anilines: 3-Iodo-4-PhenylquinolineCyclization Org. Synth. Vol. 89, p. 294 · Chen et al.
  8. 5-endo-trig cyclization of 1,1-difluoro-1-alkenes: synthesis of 3-butyl-2-fluoro-1-tosylindoleCyclization Org. Synth. Vol. 83, p. 111 · Ichikawa et al.
  9. Vinyl radical cyclization via addition of tin radicals to triple bonds: 3-methylene-4-isopropyl-1,1-cyclopentanedicarboxylic acid, dimethyl esterCyclization Org. Synth. Coll. Vol. 8, p. 381; Vol. 66, p. 75 · Mook and Sher