chempirical
Reaction database

Addition reactions

3,374 reactions: 10 worked examples with a reagent table you can scale, 503 named reactions and 2,861 checked procedures from Organic Syntheses.

25–39 of 39

  1. Palladium-catalyzed 1,4-Addition of Terminal Alkynes to Conjugated EnonesAddition Org. Synth. Vol. 91, p. 72 · Zhou et al.
  2. Palladium(0)-catalyzed syn-1,4-addition of carboxylic acids to cyclopentadiene monoepoxide: cis-3-acetoxy-5-hydroxycyclopent-1-eneAddition Org. Synth. Coll. Vol. 8, p. 13; Vol. 67, p. 114 · Deardorff and Myles
  3. Photoinduced-addition of methanol to (5S)-(5-O-tert-butyldimethylsiloxymethyl)furan-2(5H)-one: (4R,5S)-4-hydroxymethyl-(5-O-tert-butyldimethylsiloxymethyl)furan-2(5H)-oneAddition Org. Synth. Vol. 75, p. 139 · Mann and Weymouth-Wilson
  4. Preparation of enantiomerically enriched (1S)-1-phenylpropan-1-amine hydrochloride by a catalytic addition of diorganozinc reagents to iminesAddition Org. Synth. Vol. 83, p. 5 · Desrosiers et al.
  5. Preparation of polyquinanes by double addition of vinyl anions to squarate esters: 4,5,6,6a-tetrahydro-3a-hydroxy-2,3-diisopropoxy-4,6a-dimethyl-1(3aH)-pentalenoneAddition Org. Synth. Coll. Vol. 9, p. 670; Vol. 74, p. 169 · Morwick and Paquette
  6. Regioselective Mannich condensation with dimethyl(methylene)ammonium trifluoroacetate: 1-(dimethylamino)-4-methyl-3-pentanoneAddition Org. Synth. Coll. Vol. 6, p. 474; Vol. 59, p. 153 · Gaudry et al.
  7. Rhodium-catalyzed enantioselective addition of arylboronic acids to in situ generated N-BOC arylimines. Preparation of (S)-tert-butyl (4-chlorophenyl)(thiophen-2-yl)methylcarbamateAddition Org. Synth. Vol. 86, p. 360 · Storgaard and Ellman
  8. Selective hydroboration of a 1,3,7-triene: homogeraniolAddition Org. Synth. Coll. Vol. 7, p. 258; Vol. 64, p. 164 · Leopold
  9. Stereoselective nickel-catalyzed 1,4-hydroboration of 1,3-dienesAddition Org. Synth. Vol. 88, p. 342 · Ely and Morken
  10. Synthesis and utilization of indium (I) iodide for in situ formation of enantioenriched allenylindium reagents and their addition to aldehydes: (2R,3S,4S)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-5-hexyn-3-olAddition Org. Synth. Vol. 79, p. 59 · Johns et al.
  11. Synthesis of tert-butyl (1S,2S)-2-methyl-3-oxo-1-phenylpropylcarbamate by asymmetric Mannich reactionAddition Org. Synth. Vol. 86, p. 11 · Yang et al.
  12. Tandem nucleophilic addition / fragmentation of vinylogous acyl triflates: 2-methyl-2-(1-oxo-5-heptynyl)-1,3-dithianeAddition Org. Synth. Vol. 88, p. 353 · Lisboa et al.
  13. Titanium-mediated addition of silyl dienol ethers to electrophilic glycine: 4-ketopipecolic acid hydrochlorideAddition Org. Synth. Coll. Vol. 9, p. 526; Vol. 71, p. 200 · Mühlemann et al.
  14. 3-Trimethylsilyl-3-buten-2-one as Michael acceptor for conjugate addition-annelation: cis-4,4a,5,6,7,8-hexahydro-4a,5-dimethyl-2(3H)-naphthalenoneAddition Org. Synth. Coll. Vol. 6, p. 666; Vol. 58, p. 158 · Boeckman et al.
  15. 3-Trimethylsilyl-3-buten-2-one: a Michael acceptorAddition Org. Synth. Coll. Vol. 6, p. 1033; Vol. 58, p. 152 · Boeckman et al.