2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline

C₁₄H₁₉N₅O₂CAS 60547-97-9289.34 g/mol

Open in Covalent MOL file

Ether Secondary amine Tertiary amine

Properties

Molecular formula: C₁₄H₁₉N₅O₂
Molar mass: 289.34 g/mol
Exact mass: 289.1539 Da
Melting point: 230–232 °C
logP: 0.47Crippen estimate
Polar surface area: 86.3 Å²
H-bond donors / acceptors: 3 / 6
Rotatable bonds: 3

Hazards

Warning

H302 Harmful if swallowed97.6% of notifiers
H315 Causes skin irritation95.1% of notifiers
H319 Causes serious eye irritation95.1% of notifiers
H335 May cause respiratory irritation92.7% of notifiers

Aggregated from 41 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number

60547-97-9

SMILES

COc1cc2nc(N3CCNCC3)[nH]c(=N)c2cc1OC

InChIKey

APKHJGDGWQDBGM-UHFFFAOYSA-N

InChI

InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18)

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

6 names

4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-
6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine
4-Amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline
4-Amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline
2-(4-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline
2-Piperazino-6,7-dimethoxy-4-quinazolinamine

Work with 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

Terazosin63590-64-760 % similar Prazosin19216-56-959 % similar Terazosin hydrochloride63074-08-858 % similar Prazosin hydrochloride19237-84-457 % similar Terazosin monohydrochloride dihydrate70024-40-755 % similar Doxazosin74191-85-855 % similar 4-Amino-2-chloro-6,7-dimethoxyquinazoline23680-84-455 % similar Doxazosin mesylate77883-43-348 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

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