Prazosin hydrochloride

C₁₉H₂₂ClN₅O₄CAS 19237-84-4419.87 g/mol

Open in Covalent MOL file

Amide Ether Tertiary amine

Properties

Molecular formula: C₁₉H₂₂ClN₅O₄
Molar mass: 419.87 g/mol
Exact mass: 419.1360 Da
Melting point: 258–259 °C (decomposes)
Water solubility: 1.4 g/L
logP: 2.04Crippen estimate
Polar surface area: 107.7 Å²
H-bond donors / acceptors: 2 / 7
Rotatable bonds: 4

Hazards

Warning

H302 Harmful if swallowed56.6% of notifiers
H315 Causes skin irritation51.3% of notifiers
H319 Causes serious eye irritation51.3% of notifiers
H335 May cause respiratory irritation50% of notifiers
H361 Suspected of damaging fertility or the unborn child92.1% of notifiers
H373 May causes damage to organs through prolonged or repeated exposure43.4% of notifiers

Aggregated from 76 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number

19237-84-4

SMILES

COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)[nH]c(=N)c2cc1OC.Cl

InChIKey

WFXFYZULCQKPIP-UHFFFAOYSA-N

InChI

InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

20 names · show all

Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-, hydrochloride (1:1)
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-, monohydrochloride
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-, monohydrochloride
Furazosin hydrochloride
2-[4-(2-Furoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline hydrochloride
CP 12299-1
Hypovase
Peripress
Hypovasole
Minipress
Deprazolin
Pratsiol
Adverszuten
Adversuten
NSC 292810
Duramipress
Sinetens
Eurex
Alpress LP
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-furan-2-yl-methanone; hydrochloride

Work with Prazosin hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Prazosin19216-56-9Free base

Similar compounds

Cyclazosin146929-33-168 % similar Terazosin hydrochloride63074-08-860 % similar Terazosin monohydrochloride dihydrate70024-40-757 % similar Doxazosin74191-85-857 % similar 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline60547-97-957 % similar Terazosin63590-64-757 % similar Doxazosin mesylate77883-43-351 % similar 1-(2-Furanylcarbonyl)piperazine hydrochloride60548-09-644 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

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