Prazosin

C19H21N5O4CAS 19216-56-9383.41 g/mol

Open in Covalent MOL file
ONNNOONHNHO
AmideEtherTertiary amine

Properties

Molecular formula
C19H21N5O4
Molar mass
383.41 g/mol
Exact mass
383.1594 Da
Melting point
279 °C
logP
1.61Crippen estimate
Polar surface area
107.7 Ų
H-bond donors / acceptors
2 / 7
Rotatable bonds
4

Hazards

Warning
Irritant (GHS07)

Aggregated from 2 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number
19216-56-9
SMILES
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)[nH]c(=N)c2cc1OC
InChIKey
IENZQIKPVFGBNW-UHFFFAOYSA-N
InChI
InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

9 names
  • Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-
  • Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-
  • Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-
  • [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone
  • Lentopres
  • 4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazinyl 2-furyl ketone
  • Furazosin
  • 2-[4-(2-Furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
  • 2-[4-(Furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine

Work with Prazosin

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Prazosin hydrochloride19237-84-4Salt

Similar compounds

Cyclazosin146929-33-165 % similar 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline60547-97-959 % similar Doxazosin74191-85-859 % similar Terazosin63590-64-759 % similar Terazosin hydrochloride63074-08-857 % similar Terazosin monohydrochloride dihydrate70024-40-755 % similar Doxazosin mesylate77883-43-352 % similar 4-Amino-2-chloro-6,7-dimethoxyquinazoline23680-84-442 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

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