Reactions · Wikipedia: Category:Name reactions ↗
Perkin rearrangement
Condensation
Overview
The Perkin rearrangement (coumarin–benzofuran ring contraction) is a rearrangement reaction in which a 2-halocoumarin in the presence of hydroxide undergoes a ring contraction to form a benzofuran. The name reaction recognizes William Henry Perkin, who first reported it in 1870. Several proposals have been made for the reaction mechanism, all of which involve initial opening of the lactone to give a carboxylate and phenolate.
Actions
- This entry doesn't have stoichiometric equivalents on file yet — the Reaction Scale Calculator needs at least one participant tagged with an equivalents value.
- Mechanism / source ↗
- View as JSON ↗
Search literature
More Condensation reactions
- 3-HYDROXY-3-METHYL-1-PHENYL-1-BUTANONE BY CROSSED ALDOL REACTION (1-Butanone, 3-hydroxy-3-methyl-1-phenyl-) Condensation
- ACYLOIN CONDENSATION BY THIAZOLIUM ION CATALYSIS: BUTYROIN (4-Octanone, 5-hydroxy-) Condensation
- ACYLOIN CONDENSATION IN WHICH CHLOROTRIMETHYLSILANE IS USED AS A TRAPPING AGENT: 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE AND 2-HYDROXYCYCLOBUTANONE (Trimethylsilane, 1-cyclobuten-1,2-ylenedioxybis- and Cyclobutanone, 2-hydroxy-) Condensation
- Aldol–Tishchenko reaction Condensation
- AMIDE FORMATION BY DECARBOXYLATIVE CONDENSATION OF HYDROXYLAMINES AND α-KETOACIDS: N-[(1S)-1 PHENYLETHYL]-BENZENEACETAMIDE Condensation
- ANTI-SELECTIVE BORON-MEDIATED ASYMMETRIC ALDOL REACTION OF CARBOXYLIC ESTERS: SYNTHESIS OF (2S, 3R)-2,4-DIMETHYL-1,3-PENTANEDIOL (1,3-Pentanediol, 2,4-dimethyl-, [S-(R*,S*)-) Condensation