Diastereoselective synthesis of protected vicinal amino alcohols: (S)-2-[(4S)-N-tert-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidinyl]-2-tert-butyldimethylsiloxyethanal from a serine-derived aldehyde
CAS index name: 3-Oxazolidinecarboxylic acid, 4-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-oxoethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, [S-(R*,R*)]-
Organic Syntheses
![Reaction scheme of Diastereoselective synthesis of protected vicinal amino alcohols: (S)-2-[(4S)-N-tert-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidinyl]-2-tert-butyldimethylsiloxyethanal from a serine-derived aldehyde from Organic Syntheses](/orgsyn-image/V77P0078.gif)
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
The compound this preparation makes is not in the catalogue, so no reagents or figures are listed here.