Synthesis of unsymmetrical biaryls using a modified Suzuki cross-coupling: 4-biphenylcarboxaldehyde
CAS index name: [1,1'-Biphenyl]-4-carboxaldehyde
Organic SynthesesCross-coupling
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
| Compound | Role | Equiv | MW (g/mol) | ρ (g/mL) | Safety |
|---|---|---|---|---|---|
| [1,1′-Biphenyl]-4-carboxaldehyde3218-36-8 · C13H10O | product | — | 182.22 | — | Warning |
Named reactions in this procedure
More cross-coupling reactions
- Accelerated Suzuki coupling via a ligandless palladium catalyst: 4-methoxy-2'-methylbiphenyl
- Alkynyl(phenyl)iodonium tosylates: preparation and stereospecific coupling with vinylcopper reagents. Formation of conjugated enynes. 1-Hexynyl(phenyl)iodonium tosylate and (E)-5-phenyldodec-5-en-7-yne
- Coupling of o-tolidine and chicago acid
- Discussion addendum for: 4-methoxy-4'-nitrophenyl. Recent advances in the Stille biaryl coupling reaction and applications in complex natural products synthesis
- Discussion Addendum for: palladium catalyzed cross-coupling of (Z)-1-heptenyldimethylsilanol with 4-iodoanisole: (Z)-(1-heptenyl)-4-methoxybenzene
- Discussion Addendum for: Suzuki-Miyaura Cross-Coupling: Preparation of 2'-Vinylacetanilide