A general procedure for Mitsunobu inversion of sterically hindered alcohols: inversion of menthol. (1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl 4-nitrobenzoate
CAS index name: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 4-nitrobenzoate, [1S-(1α,2α,5β)]-
Organic SynthesesSubstitution
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
The compound this preparation makes is not in the catalogue, so no reagents or figures are listed here.
Named reactions in this procedure
More substitution reactions
- Indium-Catalyzed Heteroaryl–Heteroaryl Bond Formation through Nucleophilic Aromatic Substitution: Preparation of 2-Methyl-3-(thien-2-yl)-1H-indole
- Nucleophilic aromatic substitution of aryl fluorides by secondary nitriles: preparation of 2-(2-methoxyphenyl)-2-methylpropionitrile
- Substitution of aryl halides with copper(I) acetylides: 2-phenylfuro[3,2-b]pyridine
- Substitution reactions of 2-benzenesulfonyl cyclic ethers: tetrahydro-2-(phenylethynyl)-2H-pyran
- Appel reaction
- Finkelstein reaction