SYNTHESIS OF FUNCTIONALIZED ENYNES BY PALLADIUM/COPPER-CATALYZED COUPLING REACTIONS OF ACETYLENES WITH (Z)-2,3-DIBROMOPROPENOIC ACID ETHYL ESTER: (Z)-2-BROMO-5-(TRIMETHYLSILYL)-2-PENTEN-4-YNOIC ACID ETHYL ESTER (2-Penten-4-ynoic acid, 2-bromo-5-(trimethylsilyl)-, ethyl ester, (Z)-)

Overview

Preparation of 2-Penten-4-ynoic acid, 2-bromo-5-(trimethylsilyl)-, ethyl ester, (Z)-. Submitted by Andrew G. Myers and Peter S. Dragovich1. DOI: 10.15227/orgsyn.072.0104.

Actions

• This entry doesn't have stoichiometric equivalents on file yet — the Reaction Scale Calculator needs at least one participant tagged with an equivalents value.
• Mechanism / source ↗
• View as JSON ↗

Search literature

• Google Scholar ↗
• PubMed ↗
• Wikipedia ↗

More Cross-coupling reactions

• 2-(4-METHOXYPHENYL)-2-CYCLOHEXEN-1-ONE: PREPARATION OF 2-IODO-2-CYCLOHEXEN-1-ONE AND SUZUKI COUPLING WITH 4-METHOXYPHENYLBORONIC ACID (2-Cyclohexen-1-one, 2-(4-methoxyphenyl)- and 2-Cyclohexen-1-one, 2-iodo-)) Cross-coupling
• ACCELERATED SUZUKI COUPLING VIA A LIGANDLESS PALLADIUM CATALYST: 4-METHOXY-2'-METHYLBIPHENYL (1,1'-Biphenyl, 4'-methoxy-2-methyl-) Cross-coupling
• ALKYNYL(PHENYL)IODONIUM TOSYLATES: PREPARATION AND STEREOSPECIFIC COUPLING WITH VINYLCOPPER REAGENTS. FORMATION OF CONJUGATED ENYNES. 1-HEXYNYL(PHENYL)IODONIUM TOSYLATE AND (E)-5-PHENYLDODEC-5-EN-7-YNE (Iodine, 1-hexynyl(4-methylbenzenesulfonato-O)phenyl- and Benzene, (1-butyl-1-octen-3-ynyl)-, (E)-) Cross-coupling
• B-PROTECTED HALOBORONIC ACIDS FOR ITERATIVE CROSS-COUPLING Cross-coupling
• Buchwald–Hartwig amination Cross-coupling
• Cadiot–Chodkiewicz coupling Cross-coupling