DIASTEREOSELECTIVE ALDOL CONDENSATION USING A CHIRAL OXAZOLIDINONE AUXILIARY: (2S*,3S*)-3-HYDROXY-3-PHENYL-2-METHYLPROPANOIC ACID (Benzenepropanoic acid, β-hydroxy-α-methyl-, [S-(R*,R*)]-)

Overview

Preparation of Benzenepropanoic acid, β-hydroxy-α-methyl-, [S-(R*,R*)]-. Submitted by James R. Gage and David A. Evans1. DOI: 10.15227/orgsyn.068.0083.

Actions

• This entry doesn't have stoichiometric equivalents on file yet — the Reaction Scale Calculator needs at least one participant tagged with an equivalents value.
• Mechanism / source ↗
• View as JSON ↗

Search literature

• Google Scholar ↗
• PubMed ↗
• Wikipedia ↗

More Condensation reactions

• 3-HYDROXY-3-METHYL-1-PHENYL-1-BUTANONE BY CROSSED ALDOL REACTION (1-Butanone, 3-hydroxy-3-methyl-1-phenyl-) Condensation
• ACYLOIN CONDENSATION BY THIAZOLIUM ION CATALYSIS: BUTYROIN (4-Octanone, 5-hydroxy-) Condensation
• ACYLOIN CONDENSATION IN WHICH CHLOROTRIMETHYLSILANE IS USED AS A TRAPPING AGENT: 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE AND 2-HYDROXYCYCLOBUTANONE (Trimethylsilane, 1-cyclobuten-1,2-ylenedioxybis- and Cyclobutanone, 2-hydroxy-) Condensation
• Aldol–Tishchenko reaction Condensation
• AMIDE FORMATION BY DECARBOXYLATIVE CONDENSATION OF HYDROXYLAMINES AND α-KETOACIDS: N-[(1S)-1 PHENYLETHYL]-BENZENEACETAMIDE Condensation
• ANTI-SELECTIVE BORON-MEDIATED ASYMMETRIC ALDOL REACTION OF CARBOXYLIC ESTERS: SYNTHESIS OF (2S, 3R)-2,4-DIMETHYL-1,3-PENTANEDIOL (1,3-Pentanediol, 2,4-dimethyl-, [S-(R*,S*)-) Condensation