Hydroxylation of enolates with oxodiperoxymolybdenum(pyridine)(hexamethylphosphoric triamide), MoO5·Py·HMPA(MoOPH): 3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

CAS index name: Bicyclo[2.2.1]heptan-2-one, 3-hydroxy-1,7,7-trimethyl-

Organic Syntheses

Procedure on orgsyn.org
Reaction scheme of Hydroxylation of enolates with oxodiperoxymolybdenum(pyridine)(hexamethylphosphoric triamide), MoO5·Py·HMPA(MoOPH): 3-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one from Organic Syntheses
Scheme as published in Org. Synth. Coll. Vol. 7, p. 277; Vol. 64, p. 127.

A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.

Reagents

CompoundRoleEquivMW (g/mol)ρ (g/mL)Safety
Pyridine110-86-1 · C5H5N product — 79.10 0.980 Flammable (GHS02)Irritant (GHS07)DangerSDS

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Google Scholar PubMed Wikipedia DOI 10.15227/orgsyn.064.0127