α-Hydroxylation of a ketone using o-iodosylbenzoic acid: α-hydroxyacetophenone via the α-hydroxy dimethylacetal

CAS index name: Ethanone, 2-hydroxy-1-phenyl-

Organic Syntheses

Reaction scheme of α-Hydroxylation of a ketone using o-iodosylbenzoic acid: α-hydroxyacetophenone via the α-hydroxy dimethylacetal from Organic Syntheses
Scheme as published in Org. Synth. Coll. Vol. 7, p. 263; Vol. 64, p. 138.

A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.

Reagents

CompoundRoleEquivMW (g/mol)ρ (g/mL)Safety
α-Hydroxyacetophenone582-24-1 · C8H8O2 product — 136.15 — Irritant (GHS07)Warning

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