Horner–Wadsworth–Emmons reaction
Named reaction
The Horner–Wadsworth–Emmons (HWE) reaction is a chemical reaction used in organic chemistry of stabilized phosphonate carbanions with aldehydes (or ketones) to produce predominantly E-alkenes.
Checked procedures in Organic Syntheses
- Preparation of Horner-Wadsworth-Emmons reagent: methyl 2-benzyloxycarbonylamino-2- (dimethoxy- phosphinyl)acetate
- SYNTHESIS OF (−)-(E,S)-3-(BENZYLOXY)-1-BUTENYL PHENYL SULFONE VIA A HORNER-WADSWORTH-EMMONS REACTION OF (−)-(S)-2-(BENZYLOXY)PROPANAL (Benzene, [[[1-methyl-3-(phenylsulfonyl)-2-propenyl]oxy]methyl]-, [S-(E)]-) from (Propanal, 2-(phenylmethoxy)-, (S)-))