Castro–Stephens coupling

Overview

The Castro–Stephens coupling is a cross coupling reaction between a copper(I) acetylide and an aryl halide in pyridine, forming a disubstituted alkyne and a copper(I) halide.

Actions

• This entry doesn't have stoichiometric equivalents on file yet — the Reaction Scale Calculator needs at least one participant tagged with an equivalents value.
• Mechanism / source ↗
• View as JSON ↗

Search literature

• Google Scholar ↗
• PubMed ↗
• Wikipedia ↗

More Cross-coupling reactions

• 2-(4-METHOXYPHENYL)-2-CYCLOHEXEN-1-ONE: PREPARATION OF 2-IODO-2-CYCLOHEXEN-1-ONE AND SUZUKI COUPLING WITH 4-METHOXYPHENYLBORONIC ACID (2-Cyclohexen-1-one, 2-(4-methoxyphenyl)- and 2-Cyclohexen-1-one, 2-iodo-)) Cross-coupling
• ACCELERATED SUZUKI COUPLING VIA A LIGANDLESS PALLADIUM CATALYST: 4-METHOXY-2'-METHYLBIPHENYL (1,1'-Biphenyl, 4'-methoxy-2-methyl-) Cross-coupling
• ALKYNYL(PHENYL)IODONIUM TOSYLATES: PREPARATION AND STEREOSPECIFIC COUPLING WITH VINYLCOPPER REAGENTS. FORMATION OF CONJUGATED ENYNES. 1-HEXYNYL(PHENYL)IODONIUM TOSYLATE AND (E)-5-PHENYLDODEC-5-EN-7-YNE (Iodine, 1-hexynyl(4-methylbenzenesulfonato-O)phenyl- and Benzene, (1-butyl-1-octen-3-ynyl)-, (E)-) Cross-coupling
• B-PROTECTED HALOBORONIC ACIDS FOR ITERATIVE CROSS-COUPLING Cross-coupling
• Buchwald–Hartwig amination Cross-coupling
• Cadiot–Chodkiewicz coupling Cross-coupling