Cross-coupling reactions
3,374 reactions: 10 worked examples with a reagent table you can scale, 503 named reactions and 2,861 checked procedures from Organic Syntheses.
1–17 of 17
- Buchwald–Hartwig aminationCross-coupling In organic chemistry, the Buchwald–Hartwig amination is a chemical reaction for the synthesis of carbon–nitrogen bonds via the palladium-catalyzed coupling reactions of amines with aryl halides.
- Cadiot–Chodkiewicz couplingCross-coupling The Cadiot–Chodkiewicz coupling in organic chemistry is a coupling reaction between a terminal alkyne and a haloalkyne catalyzed by a copper(I) salt such as copper(I) bromide and an amine base.
- Castro–Stephens couplingCross-coupling The Castro–Stephens coupling is a cross coupling reaction between a copper(I) acetylide and an aryl halide in pyridine, forming a disubstituted alkyne and a copper(I) halide.
- Chan–Lam couplingCross-coupling The Chan–Lam coupling reaction, also known as the Chan–Evans–Lam coupling, is a cross-coupling reaction between an aryl boronic acid and an alcohol or an amine to form the corresponding secondary aryl amines or aryl ethers, respectively.
- Fukuyama couplingCross-coupling The Fukuyama coupling is a coupling reaction taking place between a thioester and an organozinc halide in the presence of a palladium catalyst.
- Glaser couplingCross-coupling The Glaser coupling is a type of coupling reaction.
- Heck reactionCross-coupling The Heck reaction (also called the Mizoroki–Heck reaction) is the chemical reaction of an unsaturated halide (or triflate) with an alkene in the presence of a base and a palladium catalyst to form a substituted alkene.
- Heck–Matsuda reactionCross-coupling The Heck–Matsuda (HM) reaction is an organic reaction and a type of palladium catalysed arylation of olefins that uses arenediazonium salts as an alternative to aryl halides and triflates.
- Hirao couplingCross-coupling In organic chemistry, Hirao coupling is a chemical reaction for the formation of carbon-phosphorus bonds using palladium cross-coupling.
- Hiyama couplingCross-coupling The Hiyama coupling is a palladium-catalyzed cross-coupling reaction of organosilanes with organic halides used in organic chemistry to form carbon–carbon bonds (C-C bonds).
- Kumada couplingCross-coupling In organic chemistry, the Kumada coupling is a type of cross coupling reaction, useful for generating carbon–carbon bonds by the reaction of a Grignard reagent and an organic halide.
- Liebeskind–Srogl couplingCross-coupling The Liebeskind–Srogl coupling reaction is an organic reaction forming a new carbon–carbon bond from a thioester and a boronic acid using a metal catalyst.
- Murahashi couplingCross-coupling The Murahashi Coupling is a cross coupling reaction.
- Negishi couplingCross-coupling The Negishi coupling is a widely employed transition metal catalyzed cross-coupling reaction.
- Sonogashira couplingCross-coupling The Sonogashira reaction is a cross-coupling reaction used in organic synthesis to form carbon–carbon bonds.
- Stille reactionCross-coupling The Stille reaction is a chemical reaction widely used in organic synthesis.
- Suzuki reactionCross-coupling The Suzuki reaction or Suzuki coupling is an organic reaction that uses a palladium complex catalyst to cross-couple a boronic acid to an organohalide.