Tool · Distillation

Pressure–Temperature Nomograph

Solve any two of compound + pressure, compound + observed boiling point, atmospheric bp + pressure, or atmospheric bp + observed bp. When the compound has Antoine constants in our database, the answer is computed exactly from log₁₀(P) = A − B/(T+C); otherwise we fall back to the compound-agnostic Clausius-Clapeyron approximation (the same one Sigma-Aldrich's tool uses).

108-88-3 CAS 108-88-3 · C7H8

Pressure	50 mmHg
Observed boiling point	36.40 °C
Boiling point at 1 atm	110.63 °C
Method	Antoine equation (compound-specific)

temp atm C = 110.6 °C is well outside the Antoine validity range (8–100 °C); value is an extrapolation.

P–T curve

Antoine validity range; the marker is your locked operating point.

Antoine: NIST WebBook constants in the antoine_parameters table. Sigma fallback: Clausius-Clapeyron at constant ΔH_vap, valid to ~±5 °C for non-polar compounds and less reliable for polar/H-bonding species — the very reason replacing Sigma's compound-agnostic nomograph with our compound-specific one is meaningful.