Tris

C4H11NO3CAS 77-86-1121.14 g/mol

Open in Covalent MOL file
NH2OHHOOH
AlcoholPrimary amine

Properties

Molecular formula
C4H11NO3
Molar mass
121.14 g/mol
Exact mass
121.0739 Da
Density
0.6181 g/mL (at 25 °C)
Melting point
171–172 °C
Boiling point
219–220 °C (at 10 Torr)
pKa
8.07
logP
-2.34Crippen estimate
Polar surface area
86.7 Ų
H-bond donors / acceptors
4 / 4
Rotatable bonds
3

Hazards

Warning
Irritant (GHS07)

Aggregated from 1,192 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number
77-86-1
SMILES
NC(CO)(CO)CO
InChIKey
LENZDBCJOHFCAS-UHFFFAOYSA-N
InChI
InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

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Names and synonyms

55 names · show all
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
  • 2-Amino-2-(hydroxymethyl)-1,3-propanediol
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol
  • Aminotris(hydroxymethyl)methane
  • Talatrol
  • THAM
  • Trimethylolaminomethane
  • Trisamine
  • Tris buffer
  • Tris(hydroxymethyl)methylamine
  • Trizma
  • Trometamol
  • Tromethamine
  • 2-Amino-2-methylol-1,3-propanediol
  • Tris(hydroxymethyl)aminomethane
  • Methanamine, 1,1,1-tris(hydroxymethyl)-
  • Aminotrimethylolmethane
  • Trometamole
  • Tromethane
  • Tris amino
  • Tris-steril
  • Tris(hydroxymethyl)methanamine
  • Pehanorm
  • Tutofusin tris
  • Trisamin
  • Tromethanmin
  • Addex-tham
  • Trisaminol
  • Tris (buffering agent)
  • Triladyl
  • Tris(methylolamino)methane
  • Trigmo base
  • TAM
  • Aminotri(hydroxymethyl)methane
  • Tris amino crystal
  • TAM (buffering agent)
  • NSC 103026
  • NSC 6365
  • NSC 65434
  • Tri(hydroxymethyl)methylamine
  • Tri amino
  • 2-Amino-1,3-dihydroxy-2-(hydroxymethyl)propane
  • 2-Amino-2-hydroxymethylpropan-1,3-diol
  • [2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amine
  • Tris base
  • Tri(hydroxymethyl)aminomethane
  • Trizma base
  • Ricrolin TE
  • A 0321
  • 2-Amino-2-(hydroxymethyl)propanediol
  • 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine
  • Tris Amino Ultra PC (J) tromethamine
  • Tris amino ultra
  • Toris amino ultra PC
  • T 1503

Safety data sheets

One stored sheet lists this compound in section 3, matched by the CAS number 77-86-1. Each row opens the sheet with its composition and PDF.

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Work with Tris

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Dinoprost tromethamine38562-01-5Salt Ketorolac tromethamine74103-07-4Salt Fosfomycin tromethamine78964-85-9Salt S-(+)-Ketoprofen trometamol156604-79-4Salt Tris(hydroxymethyl)aminomethane hydrochloride1185-53-1Salt Carboprost tromethamine58551-69-2Salt Lodoxamide tromethamine63610-09-3Salt Tris-acetate6850-28-8Salt Phosphoric acid, mono(4-nitrophenyl) ester, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:2)68189-42-4Salt

Similar compounds

[1-Aminocyclopentyl]methanol10316-79-765 % similar 2-Amino-2-ethyl-1,3-propanediol115-70-861 % similar 2-Amino-2-methyl-1,3-propanediol115-69-542 % similar Aminomethyl propanol124-68-542 % similar Pentaerythritol115-77-540 % similar 1,1-Cyclopropanedimethanol39590-81-335 % similar Trimethylolethane77-85-035 % similar Fingolimod162359-55-934 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

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