Triamcinolone acetonide

C₂₄H₃₁FO₆CAS 76-25-5434.50 g/mol

Open in Covalent MOL file

Acetal Alcohol Alkene Alkyl halide Ether Ketone

Properties

Molecular formula: C₂₄H₃₁FO₆
Molar mass: 434.50 g/mol
Exact mass: 434.2105 Da
Melting point: 293 °C
logP: 2.42Crippen estimate
Polar surface area: 93.1 Å²
H-bond donors / acceptors: 2 / 6
Rotatable bonds: 2
Stereocentres: R, S, S, S, R, S, S, Sin SMILES atom order

Hazards

Danger

H302 Harmful if swallowed12.7% of notifiers
H360 May damage fertility or the unborn child83.6% of notifiers
H361 Suspected of damaging fertility or the unborn child12.7% of notifiers
H372 Causes damage to organs through prolonged or repeated exposure10.9% of notifiers

Aggregated from 55 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P260, P264, P270, P280, P301+P317, P318, P319, P330, P405, P501

Identifiers

CAS number

76-25-5

SMILES

CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1

InChIKey

YNDXUCZADRHECN-JNQJZLCISA-N

InChI

InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

64 names · show all

Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Aristocort acetonide
Aristoderm
9α-Fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
9α-Fluoro-16α-hydroxyprednisolone 16α,17α-acetonide
Kenalog
Triamcinolone 16,17-acetonide
Paralen
Kenacort A
9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide
9-Fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
9-Fluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
Volon A
Adcortyl A
Solodelf
Vetalog
Omcilon A
Queyanshusong A
Triamcinolone 16α,17α-acetonide
Kenalog 10
Trianopollon
Azmacort
Kenacort 80
Aftach
Nasacort
Triam
Extracort
Trymex
TAC 40
Tramacin
Respicort
Rineton
TAC 3
Ftorocort
Triamonide 40
Volonimat
Tricinolon
Triacet
Ledercort cream
Delphicort
Adcortyl
Tri-nasal
NSC 21916
Triamcort-depot
Aristocort A
Kenacort A 40
Aristicort
Lichtena
Triamhexal
Vetazine
Kenalog 40
Tamceton
Berlicort
Kenacort 40
Pol'kortolon
Triakort
Trivaris
Triesence
I-Vation
Valon A 10
MaQuaid
Rheudenolone

Work with Triamcinolone acetonide

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

(11β,16α)-21-(Acetyloxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione3870-07-381 % similar Fluocinolone 16,17-acetonide67-73-277 % similar Triamcinolone124-94-772 % similar Betamethasone378-44-968 % similar Dexamethasone50-02-268 % similar Betamethasone valerate2152-44-566 % similar Fluocinonide356-12-765 % similar Clobetasol25122-41-261 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Same formula

Dexamethasone acetate1177-87-3 Flunisolide3385-03-3 Betamethasone acetate987-24-6

Elsewhere

PubChem CAS Common Chemistry NIST WebBook