Dexamethasone
Properties
- Molecular formula
- C22H29FO5
- Molar mass
- 392.47 g/mol
- Exact mass
- 392.1999 Da
- Melting point
- 262–264 °C
- Water solubility
- 89 mg/L (25 °C)
- logP
- 1.90Crippen estimate
- Polar surface area
- 94.8 Ų
- H-bond donors / acceptors
- 3 / 5
- Rotatable bonds
- 2
- Stereocentres
- R, S, S, S, R, S, S, Rin SMILES atom order
Hazards
Danger
- H315 Causes skin irritation24.6% of notifiers
- H317 May cause an allergic skin reaction26.2% of notifiers
- H319 Causes serious eye irritation25.1% of notifiers
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled24.1% of notifiers
- H335 May cause respiratory irritation24.1% of notifiers
- H360 May damage fertility or the unborn child51.9% of notifiers
- H360D May damage the unborn child12.8% of notifiers
- H373 May causes damage to organs through prolonged or repeated exposure35.8% of notifiers
- H410 Very toxic to aquatic life with long lasting effects33.2% of notifiers
Aggregated from 187 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P203, P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P391, P403, P403+P233, P405, P501
Identifiers
CAS number
50-02-2SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COInChIKey
UREBDLICKHMUKA-CXSFZGCWSA-NInChI
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1Weigh it out
Type any one amount. The others follow from the molar mass.
Names and synonyms
95 names · show all
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11β,16α)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-
- (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- MK 125
- Corsone
- Decaderm
- Decadron
- Decasone
- 1-Dehydro-16α-methyl-9α-fluorohydrocortisone
- Dergramin
- Deronil
- Desadrene
- Dexacort
- Dexa-cortidelt
- Dexadeltone
- Dexameth
- Dextelan
- 9α-Fluoro-16α-methylprednisolone
- 9α-Fluoro-16α-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
- 9α-Fluoro-16α-methyl-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione
- 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
- Gammacorten
- Hexadecadrol
- Hexadrol
- 16α-Methyl-9α-fluoro-δ1-hydrocortisone
- 16α-Methyl-9α-fluoroprednisolone
- 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
- 16α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
- Maxidex
- Millicorten
- Oradexon
- Superprednol
- Deltafluorene
- Dexamethasone alcohol
- Dexason
- Prednisolon F
- Dexa-scheroson
- Dexalona
- Aphtasolon
- Desameton
- Calonat
- Dekacort
- Visumetazone
- Prednisolone F
- Dexapolcort
- Azium
- HL-Dex
- Fluorocort
- Dexaprol
- Dexaltin
- Aphthasolone
- Dexasone
- Dexonium
- Luxazone
- Decalix
- Lokalison F
- Dexa-sine
- Aeroseb-dex
- Dinormon
- Pet-derm III
- Deseronil
- Dexacortal
- Dexafarma
- Dexapos
- Dexacortin
- Cortisumman
- Loverine
- Dexinoral
- Fluormone
- Dexamonozon
- Isopto-dex
- Dexa-mamallet
- Decacort
- Adexone
- NSC 34521
- Decadron A
- Delipos
- Gentalipos
- Surodex
- Etacortilen
- Dexone
- Diodex
- Posurdex
- Dexmethsone
- Dekort
- Ozurdex
- Dexaratiopharm
- Dexaven
- Dexium
- Minidex
- Fluormethylprednisolone
- DEX
- Oftan
- Neofordex
Work with Dexamethasone
Similar compounds
Triamcinolone124-94-787 % similar
Clobetasol25122-41-284 % similar
Dexamethasone acetate1177-87-379 % similar
Betamethasone acetate987-24-679 % similar
Beclomethasone4419-39-078 % similar
Flumetasone2135-17-376 % similar
Diflorasone2557-49-576 % similar
Betamethasone sodium phosphate151-73-572 % similar
Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds