Amantadine hydrochloride

C₁₀H₁₈ClNCAS 665-66-7187.71 g/mol

Open in Covalent MOL file

Primary amine

Properties

Molecular formula: C₁₀H₁₈ClN
Molar mass: 187.71 g/mol
Exact mass: 187.1128 Da
Melting point: 359–360 °C
logP: 2.34Crippen estimate
Polar surface area: 26.0 Å²
H-bond donors / acceptors: 1 / 1
Rotatable bonds: 0

Hazards

Danger

H302 Harmful if swallowed99.5% of notifiers
H314 Causes severe skin burns and eye damage75.2% of notifiers
H318 Causes serious eye damage73.3% of notifiers
H336 May cause drowsiness or dizziness22.4% of notifiers
H361 Suspected of damaging fertility or the unborn child77.6% of notifiers
H412 Harmful to aquatic life with long lasting effects75.2% of notifiers

Aggregated from 210 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P319, P321, P330, P363, P403+P233, P405, P501

Identifiers

CAS number

665-66-7

SMILES

Cl.NC12CC3CC(CC(C3)C1)C2

InChIKey

WOLHOYHSEKDWQH-UHFFFAOYSA-N

InChI

InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

26 names · show all

Tricyclo[3.3.1.13,7]decan-1-amine, hydrochloride (1:1)
1-Adamantanamine, hydrochloride
Tricyclo[3.3.1.13,7]decan-1-amine, hydrochloride
Adamantanamine hydrochloride
EXP 105-1
NSC 83653
Symmetrel
Aminoadamantane hydrochloride
Mydantane
Midantane
1-Aminoadamantane hydrochloride
1-Adamantylamine hydrochloride
Adamantylamine hydrochloride
1-Adamantamine hydrochloride
Virasol
Symadine
Amazolon
Mantadine
Virofral
Mantadan
Midantan
Mantadix
Adamin
Adamine
ADS 5102
Gocovri

Work with Amantadine hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Amantadine768-94-5Free base Amantadine sulfate31377-23-8Salt

Similar compounds

Bicyclo[1.1.1]pentan-3-amine,hydrochloride22287-35-078 % similar Bicyclo(1.1.1)pentan-1-amine177287-49-961 % similar Adamantane-1,3-diamine10303-95-460 % similar Memantine hydrochloride41100-52-146 % similar 3-Amino-1-adamantanol702-82-946 % similar Rimantadine hydrochloride1501-84-444 % similar Adamantane-1-carboxamidine hydrochloride50417-14-643 % similar Tris(hydroxymethyl)aminomethane hydrochloride1185-53-139 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Same formula

2-Aminoadamantane hydrochloride10523-68-9

Elsewhere

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