Hydroxyproline
Properties
- Molecular formula
- C5H9NO3
- Molar mass
- 131.13 g/mol
- Exact mass
- 131.0582 Da
- Melting point
- 274 °C
- logP
- -1.21Crippen estimate
- Polar surface area
- 69.6 Ų
- H-bond donors / acceptors
- 3 / 3
- Rotatable bonds
- 1
- Stereocentres
- S, Rin SMILES atom order
Hazards
Warning
- H315 Causes skin irritation10.7% of notifiers
- H319 Causes serious eye irritation10.7% of notifiers
- H335 May cause respiratory irritation10.7% of notifiers
Aggregated from 28 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Identifiers
CAS number
51-35-4SMILES
O=C(O)[C@@H]1C[C@@H](O)CN1InChIKey
PMMYEEVYMWASQN-DMTCNVIQSA-NInChI
InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1Weigh it out
Type any one amount. The others follow from the molar mass.
Names and synonyms
33 names · show all
- L-Proline, 4-hydroxy-, (4R)-
- Proline, 4-hydroxy-, L-
- L-Proline, 4-hydroxy-, trans-
- (4R)-4-Hydroxy-L-proline
- Hydroxy-L-proline
- 4-Hydroxyproline
- 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid
- Hypro
- δ-Hydroxyproline
- 4-Hydroxy-L-proline
- trans-4-Hydroxyproline
- trans-4-Hydroxy-L-proline
- trans-L-Hydroxyproline
- 4-trans-Hydroxy-L-proline
- L-4-Hydroxyproline
- Ls-hydroxyproline
- (2S,4R)-(-)-4-Hydroxyproline
- L-Hydroxyproline
- L-trans-4-Hydroxyproline
- (R)-4-Hydroxy-(S)-proline
- (S)-Hydroxyproline
- L-Hypro
- (-)-4-Hydroxy-2-pyrrolidinecarboxylic acid
- trans-L-4-Hydroxyproline
- (R)-4-Hydroxy-L-proline
- Proline, 4-hydroxy-
- (2S,4R)-4-Hydroxyproline
- NSC 46704
- 4-Hydroxy-(S)-proline
- 4(R)-Hydroxyproline
- (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid
- (4R,2S)-Hydroxyproline
- trans-(2S,4R)-4-Hydroxy-L-proline
Work with Hydroxyproline
Stereoisomers, salts and isotopologues
The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.
(2R,4S)-4-Hydroxypyrrolidine-2-carboxylic acid3398-22-9Enantiomer
cis-4-Hydroxy-L-proline618-27-9Diastereomer
cis-4-Hydroxy-D-proline2584-71-6Diastereomer
(2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride77449-94-6Salt, diastereomer
(2R,4S)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride142347-81-7Salt, enantiomer
Similar compounds
(2R,4S)-4-Fluoropyrrolidine-2-carboxylic acid131176-02-860 % similar
(2S,4S)-4-Fluoro-pyrrolidine-2-carboxylic acid2438-57-560 % similar
(4R)-4-Fluoro-L-proline2507-61-160 % similar
(4S)-4-Cyclohexyl-L-proline103201-78-155 % similar
(4R)-4-Fluoro-L-proline hcl60604-36-655 % similar
3-Hydroxycyclobutanecarboxylic acid194788-10-850 % similar
(4R)-4-(1,1-Dimethylethoxy)-L-proline79775-07-850 % similar
trans-4-Cyclohexyl-L-proline monohydrochloride90657-55-950 % similar
Tanimoto similarity of circular fingerprints over the whole catalogue.