cis-4-Hydroxy-D-proline

C5H9NO3CAS 2584-71-6131.13 g/mol

Open in Covalent MOL file
OHOOHHN
AlcoholCarboxylic acidSecondary amine

Properties

Molecular formula
C5H9NO3
Molar mass
131.13 g/mol
Exact mass
131.0582 Da
Melting point
240 °C
logP
-1.21Crippen estimate
Polar surface area
69.6 Ų
H-bond donors / acceptors
3 / 3
Rotatable bonds
1
Stereocentres
R, Rin SMILES atom order

Hazards

Warning
Irritant (GHS07)

Aggregated from 5 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number
2584-71-6
SMILES
O=C(O)[C@H]1C[C@@H](O)CN1
InChIKey
PMMYEEVYMWASQN-QWWZWVQMSA-N
InChI
InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m1/s1

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

14 names · show all
  • D-Proline, 4-hydroxy-, (4R)-
  • Proline, 4-allo-hydroxy-, D-
  • D-Proline, 4-hydroxy-, cis-
  • (4R)-4-Hydroxy-D-proline
  • 4-Allo-Hydroxy-D-proline
  • D-Allo-Hydroxyproline
  • 4-Hydroxy-D-alloproline
  • D-Allo-4-Hydroxyproline
  • (R)-Allo-Hydroxyproline
  • D-cis-4-Hydroxyproline
  • NSC 524341
  • (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid
  • 4-(R)-Hydroxypyrrolidine-2-(R)-carboxylic acid
  • (2R,4R)-4-Hydroxyproline

Work with cis-4-Hydroxy-D-proline

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

cis-4-Hydroxy-L-proline618-27-9Enantiomer Hydroxyproline51-35-4Diastereomer (2R,4S)-4-Hydroxypyrrolidine-2-carboxylic acid3398-22-9Diastereomer (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride77449-94-6Salt (2R,4S)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride142347-81-7Salt, diastereomer

Similar compounds

(2R,4S)-4-Fluoropyrrolidine-2-carboxylic acid131176-02-860 % similar (2S,4S)-4-Fluoro-pyrrolidine-2-carboxylic acid2438-57-560 % similar (4R)-4-Fluoro-L-proline2507-61-160 % similar (4S)-4-Cyclohexyl-L-proline103201-78-155 % similar (4R)-4-Fluoro-L-proline hcl60604-36-655 % similar 3-Hydroxycyclobutanecarboxylic acid194788-10-850 % similar (4R)-4-(1,1-Dimethylethoxy)-L-proline79775-07-850 % similar trans-4-Cyclohexyl-L-proline monohydrochloride90657-55-950 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Same formula

5-Aminolevulinic acid106-60-5 (S)-Morpholine-3-carboxylic acid106825-79-0 N-Acetylalanine1115-69-1 3-Aminotetrahydrofuran-3-carboxylic acid125218-55-5 N-Acetyl-D-alanine19436-52-3 N-Acetyl-beta-alanine3025-95-4 Ethyl N-formylglycinate3154-51-6

Elsewhere

PubChem CAS Common Chemistry NIST WebBook