Hydroxycamptothecin
Properties
- Molecular formula
- C20H16N2O5
- Molar mass
- 364.36 g/mol
- Exact mass
- 364.1059 Da
- Melting point
- 268–270 °C
- logP
- 1.79Crippen estimate
- Polar surface area
- 101.7 Ų
- H-bond donors / acceptors
- 2 / 6
- Rotatable bonds
- 1
- Stereocentres
- Sin SMILES atom order
Hazards
Warning
- H315 Causes skin irritation97.4% of notifiers
- H319 Causes serious eye irritation97.4% of notifiers
- H335 May cause respiratory irritation97.4% of notifiers
Aggregated from 39 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Identifiers
CAS number
19685-09-7SMILES
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(O)ccc3nc2-1InChIKey
HAWSQZCWOQZXHI-FQEVSTJZSA-NInChI
InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1Weigh it out
Type any one amount. The others follow from the molar mass.
Names and synonyms
11 names
- 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (4S)-
- Camptothecine, 10-hydroxy-
- 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (S)-
- (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- 10-Hydroxycamptothecine
- 10-Hydroxycamptothecin
- (S)-10-Hydroxycamptothecin
- NSC 107124
- (+)-10-Hydroxycamptothecin
- ChEMBL 273862
- 10-HCPT
Work with Hydroxycamptothecin
Stereoisomers, salts and isotopologues
The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.
Similar compounds
Camptothecin7689-03-480 % similar
Sn-3886639-52-374 % similar
9-Aminocamptothecin91421-43-168 % similar
Topotecan123948-87-868 % similar
9-Methoxycamptothecin39026-92-167 % similar
Topotecan hydrochloride119413-54-665 % similar
9-Nitrocamptothecin91421-42-063 % similar
7-Ethylcamptothecin78287-27-163 % similar
Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds