Tipifarnib
Properties
- Molecular formula
- C27H22Cl2N4O
- Molar mass
- 489.40 g/mol
- Exact mass
- 488.1171 Da
- Melting point
- 234 °C
- logP
- 5.50Crippen estimate
- Polar surface area
- 65.8 Ų
- H-bond donors / acceptors
- 1 / 3
- Rotatable bonds
- 4
- Stereocentres
- Rin SMILES atom order
Hazards
Warning
- H302 Harmful if swallowed33.3% of notifiers
- H315 Causes skin irritation100% of notifiers
- H319 Causes serious eye irritation100% of notifiers
- H335 May cause respiratory irritation66.7% of notifiers
- H373 May causes damage to organs through prolonged or repeated exposure33.3% of notifiers
Aggregated from 3 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Identifiers
CAS number
192185-72-1SMILES
Cn1cncc1[C@@](N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2CInChIKey
PLHJCIYEEKOWNM-HHHXNRCGSA-NInChI
InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1Weigh it out
Type any one amount. The others follow from the molar mass.
Names and synonyms
5 names
- 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
- 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
- (R)-(+)-R 115777
- Zarnestra
- 2: PN: WO2019129231 SEQID: 3 claimed sequence