Metformin hydrochloride

C₄H₁₂ClN₅CAS 1115-70-4165.63 g/mol

Open in Covalent MOL file

Guanidine

Properties

Molecular formula: C₄H₁₂ClN₅
Molar mass: 165.63 g/mol
Exact mass: 165.0781 Da
Melting point: 232 °C
pKa: 12.4
logP: -0.61Crippen estimate
Polar surface area: 89.0 Å²
H-bond donors / acceptors: 4 / 2
Rotatable bonds: 0

Hazards

Warning

H302 Harmful if swallowed99.6% of notifiers
H315 Causes skin irritation42.3% of notifiers
H319 Causes serious eye irritation64.5% of notifiers
H335 May cause respiratory irritation11.7% of notifiers
H412 Harmful to aquatic life with long lasting effects15.1% of notifiers

Aggregated from 265 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number

1115-70-4

SMILES

CN(C)C(=N)NC(=N)N.Cl

InChIKey

OETHQSJEHLVLGH-UHFFFAOYSA-N

InChI

InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

70 names · show all

Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1)
Biguanide, 1,1-dimethyl-, monohydrochloride
Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride
Biguanide, 1,1-dimethyl-, hydrochloride
N,N-Dimethylbiguanide hydrochloride
1,1-Dimethylbiguanide hydrochloride
Meguan
N1,N1-Dimethylbiguanide hydrochloride
Diabefagos
Glucophage
Glyformin
LA 6023
Dabex
Denkaform
Dextin
Diabetmin
Diabex
Apophage
Benofomin
Diformin retard
Dimefor
Fornidd
Geamet
Glucaminol
Glucofago
Glucomet
Glucomine
Glucoform
Glucomin
Gluconil
Glucophage 850
Glucophage forte
Glucophage-mite
Glucophage retard
Gludepatic
Glufor
Gluformin
Glumeformin
Glumin
Glupermin
Glyciphage
Glycon
Metforal
Metomin
Miformin
Orabet
Siamformet
Walaphage
Diaformin
Diformin
Glyceriphage
Diabetosan
Dialon
Glucophage XR
N,N-Dimethylbiguanidinium chloride
Apo-metformin
Brot
Glumetza
Glifage
Glucophage SR
Melbin
N,N-Dimethylbiguanidine monohydrochloride
Glucoformin
Riomet
Glumin XR
Metgluco
Neodipa
Diabetmim
FORTAMET
Obimat-SR

Work with Metformin hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Metformin657-24-9Free base Metformin-D6, hydrochloride1185166-01-1

Similar compounds

Moroxydine hydrochloride3160-91-651 % similar Methylguanidine hydrochloride21770-81-046 % similar Methylguanidine hydrochloride22661-87-646 % similar Moroxydine3731-59-743 % similar Aminoguanidinium chloride16139-18-741 % similar Aminoguanidinium chloride1937-19-541 % similar Amidinothiourea2114-02-535 % similar Dodecylguanidine hydrochloride13590-97-135 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Elsewhere

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