Enantioselective hydrolysis of cis-3,5-diacetoxycyclopentene: (1R,4S)-(+)-4-hydroxy-2-cyclopentenyl acetate

CAS index name: 4-Cyclopentene-1,3-diol, monoacetate, (1R-cis)-

Organic SynthesesHydrolysis

Reaction scheme of Enantioselective hydrolysis of cis-3,5-diacetoxycyclopentene: (1R,4S)-(+)-4-hydroxy-2-cyclopentenyl acetate from Organic Syntheses
Scheme as published in Org. Synth. Coll. Vol. 9, p. 487; Vol. 73, p. 25.

A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.

Reagents

CompoundRoleEquivMW (g/mol)ρ (g/mL)Safety
rac-(1R,4S)-4-Hydroxycyclopent-2-en-1-yl acetate60410-16-4 · C7H10O3 product — 142.15 — Irritant (GHS07)Warning

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