Pyridine-derived triflating reagents: N-(2-pyridyl)-triflimide and N-(5-chloro-2-pyridyl)triflimide

CAS index name: Methanesulfonamide, 1,1,1-trifluoro-N-2-pyridinyl-N-[(trifluoromethyl)sulfonyl]-] and Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-

Organic Syntheses

Procedure on orgsyn.org
Reaction scheme of Pyridine-derived triflating reagents: N-(2-pyridyl)-triflimide and N-(5-chloro-2-pyridyl)triflimide from Organic Syntheses
Scheme as published in Org. Synth. Coll. Vol. 9, p. 165; Vol. 74, p. 77.

A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.

Reagents

CompoundRoleEquivMW (g/mol)ρ (g/mL)Safety
Comins' reagent145100-51-2 · C7H3ClF6N2O4S2 product — 392.67 — Irritant (GHS07)Warning

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Google Scholar PubMed Wikipedia DOI 10.15227/orgsyn.074.0077