Synthesis of functionalized enynes by palladium/copper-catalyzed coupling reactions of acetylenes with (Z)-2,3-dibromopropenoic acid ethyl ester: (Z)-2-bromo-5-(trimethylsilyl)-2-penten-4-ynoic acid ethyl ester

CAS index name: 2-Penten-4-ynoic acid, 2-bromo-5-(trimethylsilyl)-, ethyl ester, (Z)-

Organic SynthesesCross-coupling

Reaction scheme of Synthesis of functionalized enynes by palladium/copper-catalyzed coupling reactions of acetylenes with (Z)-2,3-dibromopropenoic acid ethyl ester: (Z)-2-bromo-5-(trimethylsilyl)-2-penten-4-ynoic acid ethyl ester from Organic Syntheses
Scheme as published in Org. Synth. Coll. Vol. 9, p. 117; Vol. 72, p. 104.

A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.

Reagents

The compound this preparation makes is not in the catalogue, so no reagents or figures are listed here.

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