Hofmann rearrangement under mildly acidic conditions using [I,I-bis(trifluoroacetoxy)]iodobenzene: cyclobutylamine hydrochloride from cyclobutanecarboxamide
CAS index name: Cyclobutanamine hydrochloride
Organic SynthesesRearrangement
![Reaction scheme of Hofmann rearrangement under mildly acidic conditions using [I,I-bis(trifluoroacetoxy)]iodobenzene: cyclobutylamine hydrochloride from cyclobutanecarboxamide from Organic Syntheses](/orgsyn-image/CV8P0132.gif)
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
The compound this preparation makes is not in the catalogue, so no reagents or figures are listed here.
More rearrangement reactions
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- Benzalpinacolone