Thiol protection with the acetamidomethyl group: S-acetamidomethyl-L-cysteine hydrochloride
CAS index name: L-Cysteine, S-[(acetylamino)methyl]-, monohydrochloride
Organic SynthesesProtection
A checked procedure from Organic Syntheses, the journal whose preparations are repeated in a second laboratory before publication. The full experimental, with amounts, hazards and characterisation data, is on orgsyn.org.
Reagents
| Compound | Role | Equiv | MW (g/mol) | ρ (g/mL) | Safety |
|---|---|---|---|---|---|
| S-(Acetamidomethyl)-L-cysteine hydrochloride28798-28-9 · C6H13ClN2O3S | product | — | 228.69 | — | — |
More protection reactions
- Mono carbamate protection of aliphatic diamines using alkyl phenyl carbonates
- Protection of alcohols using 2-benzyloxy-1-methylpyridinium trifluoromethanesulfonate: methyl (R)-(-)-3-benzyloxy-2-methyl propanoate
- Protection of diols with 4-(tert-butyldimethylsilyloxy)benzylidene acetal and its deprotection: ((4-((4R,5R)-4,5-diphenyl-1,3-dioxolan-2-yl)phenoxy)(tert- butyl)dimethylsilane)
- Reagent for Divalent Sulfur Protection: Preparation of 4-Methylbenzenesulfonothioic Acid, S-[[[(1,1-Dimethylethyl)-Dimethylsilyl]oxy]methyl] Ester
- Selective protection of 1,3-diols at the more hindered hydroxy group: 3-(methoxymethoxy)-1-butanol