Homo-Favorskii rearrangement

Named reactionRearrangement

The homo Favorskii rearrangement is the rearrangement of β-halo ketones and cyclobutanones, which in ring systems may yield ring contraction. This rearrangement takes place in the presence of a base, yielding a carboxylic acid derivative corresponding to the nucleophile (most often the base itself). E1cb will occur if α-carbon adjacent to the halogen atom has hydrogens on it.

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