Ruxolitinib

C17H18N6CAS 941678-49-5306.37 g/mol

NNNNHNN
Nitrile

Properties

Molecular formula
C17H18N6
Molar mass
306.37 g/mol
Exact mass
306.1593 Da
logP
3.42Crippen estimate
Polar surface area
83.2 Ų
H-bond donors / acceptors
1 / 4
Rotatable bonds
4
Stereocentres
Rin SMILES atom order

Identifiers

CAS number
941678-49-5
SMILES
N#CC[C@H](C1CCCC1)n1cc(-c2nc[nH]c3nccc2-3)cn1
InChIKey
HFNKQEVNSGCOJV-OAHLLOKOSA-N
InChI
InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1

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Names and synonyms

6 names
  • 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βR)-
  • (βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
  • INCB 018424
  • (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
  • INC 424
  • (R)-3-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-cyclopentylpropanenitrile

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Similar compounds

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

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