chempirical

Dapsone

C12H12N2O2SCAS 80-08-0248.30 g/mol

Open in Covalent MOL file
H2NSOONH2
Primary amineSulfone

Properties

Molecular formula
C12H12N2O2S
Molar mass
248.30 g/mol
Exact mass
248.0619 Da
Density
1.39 g/mL
Melting point
175–176 °C
pKa
2.41 (conjugate acid)
Flash point
160 °C
Water solubility
380 mg/L (37 °C)
logP
1.68Crippen estimate
Polar surface area
86.2 Ų
H-bond donors / acceptors
2 / 4
Rotatable bonds
2

Hazards

Warning
Irritant (GHS07)

Harmonised EU classification (CLP Annex VI), via PubChem.

Precautionary statements

P264, P270, P301+P317, P330, P501

Identifiers

CAS number
80-08-0
SMILES
Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1
InChIKey
MQJKPEGWNLWLTK-UHFFFAOYSA-N
InChI
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

Weigh it out

Type any one amount. The others follow from the molar mass and density.

Names and synonyms

72 names · show all
  • Atrisone
  • Benzenamine, 4,4′-sulfonylbis-
  • Aniline, 4,4′-sulfonyldi-
  • 4,4′-Sulfonylbis[benzenamine]
  • 1358F
  • F 1358
  • Avlosulfon
  • Avlosulfone
  • Bis(4-aminophenyl) sulfone
  • Croysulfone
  • DADPS
  • DDS
  • p,p′-Diaminodiphenyl sulfone
  • 4,4′-Diaminodiphenyl sulfone
  • Di(p-aminophenyl) sulfone
  • Diaphenylsulfone
  • Di(4-aminophenyl)sulfone
  • Diphenasone
  • Diphone
  • Disulone
  • DSS
  • Dumitone
  • Eporal
  • Metabolite C
  • Novophone
  • Sulfona-mae
  • p,p′-Sulfonyldianiline
  • 4,4′-Sulfonyldianiline
  • Sulphadione
  • 4,4′-Sulphonyldianiline
  • Udolac
  • DDS (pharmaceutical)
  • Bis(p-aminophenyl) sulfone
  • 4-Aminophenyl sulfone
  • 4,4′-Sulfonylbisbenzamine
  • 1,1′-Sulfonylbis[4-aminobenzene]
  • Sulfona
  • p-Aminophenyl sulfone
  • Diaphenylsulfon
  • Dapson
  • 4,4′-Sulfonylbisaniline
  • HT 976
  • Araldite HT 976
  • Sumicure S
  • Hardener HT 976
  • 4,4′-Dapsone
  • HT 9664
  • Seikacure S
  • NSC 6091
  • HY 976
  • Aradur 976-1
  • HT 976-1
  • Servidapson
  • 4,4′-DDS
  • 4,4′-Sulfonyldiphenylamine
  • DADFS
  • HB-MC-GE 40
  • HB-MC-GE 45
  • Lapox K 10
  • Aczone
  • Aradur 9664-1
  • 4-(4-Aminophenylsulfonyl)benzenamine
  • 4-(4-Aminophenyl)sulfonylaniline
  • Aradur 9761-1
  • 4,4′-Diaminobiphenyl sulfone
  • HEW 62
  • Aradur 976
  • D 0089
  • Aradur 9664-1NL
  • K 10
  • 44DDS
  • 4,4'-Diaminodiphenylsulfone

Reactions

Work with Dapsone

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

4,4′-[Sulfonylbis(4,1-phenyleneoxy)]bis[benzenamine]13080-89-275 % similar Sulfanilamide63-74-158 % similar Sulfanilic acid121-57-356 % similar 4-(Methylsulfonyl)aniline5470-49-556 % similar 4,4′-Diaminobenzenesulfonanilide16803-97-752 % similar Sodium p-aminobenzenesulfonate515-74-252 % similar P-Phenylenediamine106-50-350 % similar Diphenyl sulfone127-63-950 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Same formula

3,3'-Sulphonyldianiline599-61-1 Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate64399-23-1 Enoximone77671-31-9 3-Amino-N-phenylbenzenesulfonamide80-21-7

Elsewhere

PubChem CAS Common Chemistry NIST WebBook