Linifanib
Properties
- Molecular formula
- C21H18FN5O
- Molar mass
- 375.41 g/mol
- Exact mass
- 375.1495 Da
- Melting point
- 209–211 °C
- logP
- 4.92Crippen estimate
- Polar surface area
- 99.3 Ų
- H-bond donors / acceptors
- 4 / 3
- Rotatable bonds
- 3
Hazards
Danger
- H361 Suspected of damaging fertility or the unborn child100% of notifiers
- H372 Causes damage to organs through prolonged or repeated exposure100% of notifiers
- H400 Very toxic to aquatic life100% of notifiers
- H410 Very toxic to aquatic life with long lasting effects100% of notifiers
Aggregated from 42 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P203, P260, P264, P270, P273, P280, P318, P319, P391, P405, P501
Identifiers
CAS number
796967-16-3SMILES
Cc1ccc(F)c(N=C(O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1InChIKey
MPVGZUGXCQEXTM-UHFFFAOYSA-NInChI
InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)Weigh it out
Type any one amount. The others follow from the molar mass.
Names and synonyms
7 names
- Linigfanib
- RG 3635
- AL 39324
- 1-[4-(3-Amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
- Urea, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methylphenyl)-
- N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methylphenyl)urea
- ABT 869
Work with Linifanib
Similar compounds
4-Bromo-1H-indazol-3-amine914311-50-532 % similar
N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N′-[4-(dimethylamino)phenyl]urea288150-92-532 % similar
4-Iodo-1H-indazol-3-amine599191-73-831 % similar
Tanimoto similarity of circular fingerprints over the whole catalogue.