Medroxyprogesterone acetate

C₂₄H₃₄O₄CAS 71-58-9386.53 g/mol

Open in Covalent MOL file

Alkene Ester Ketone

Properties

Molecular formula: C₂₄H₃₄O₄
Molar mass: 386.53 g/mol
Exact mass: 386.2457 Da
Melting point: 207–209 °C
Water solubility: < 1 g/L (22.8 °C)
logP: 4.66Crippen estimate
Polar surface area: 60.4 Å²
H-bond donors / acceptors: 0 / 4
Rotatable bonds: 2
Stereocentres: R, S, R, S, R, S, Sin SMILES atom order

Hazards

Danger

H302 Harmful if swallowed19.3% of notifiers
H312 Harmful in contact with skin19.3% of notifiers
H332 Harmful if inhaled18.7% of notifiers
H351 Suspected of causing cancer98.8% of notifiers
H360 May damage fertility or the unborn child55.4% of notifiers
H362 May cause harm to breast-fed children15.7% of notifiers
H413 May cause long lasting harmful effects to aquatic life17.5% of notifiers

Aggregated from 166 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P260, P261, P263, P264, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P317, P318, P321, P330, P362+P364, P405, P501

Identifiers

CAS number

71-58-9

SMILES

CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

InChIKey

PSGAAPLEWMOORI-PEINSRQWSA-N

InChI

InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

76 names · show all

Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6α)-
Pregn-4-ene-3,20-dione, 17-hydroxy-6α-methyl-, acetate
Progesterone, 17-hydroxy-6α-methyl-, acetate
(6α)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione
17α-Acetoxy-6α-methylpregn-4-ene-3,20-dione
17α-Acetoxy-6α-methylprogesterone
Depo-provera
Farlutin
17α-Hydroxy-6α-methylpregn-4-ene-3,20-dione acetate
17α-Hydroxy-6α-methylprogesterone acetate
MAP
6α-Methyl-17α-acetoxy-δ4-pregnene-3,20-dione
6α-Methyl-17α-acetoxypregn-4-ene-3,20-dione
6α-Methyl-17α-hydroxyprogesterone acetate
MPA
Oragest
Perlutex
Provera
Repromix
U 8839
Depomedroxyprogesterone acetate
6α-Methyl-17-acetoxyprogesterone
Veramix
Progevera
Lutopolar
Lutoral
Metigestrona
Proverone
Sirprogen
Gestapuran
Prodasone
Progestalfa
6α-Methyl-17α-Hydroxy-4-pregnene-3,20-dione acetate
Depot-medroxyprogesterone acetate
DMPA
Medroxyprogesterone 17-acetate
Repromap
17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione 17-acetate
Clinovir
Depo-progestin
Farlutal
MAP (steroid)
Cycrin
Hysron
Medroprogesterone acetate
Indivina
CBP 1011
Colirest
Hematrol
Perlutex leo
Amen
Depo-prodasone
Meprate
Asconale
Med-pro
Progeston
MPA Gyn 5
Ralovera
Aragest 5
Clinofem
Novo-medrone
Aragest
Curretab
Sodelut G
Depo-clinovir
Nadigest
Nidaxin
G-Farlutal
Depo-promone
NSC 21171
NSC 26386
Depo-ralovera
Progespon
6α-Methyl-17R-hydroxyprogesterone acetate
Depo-SubQ provera 104
Prempack C

Work with Medroxyprogesterone acetate

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

17-Acetoxyisopregn-4-ene-3,20-dione17308-02-071 % similar Progesterone acetate302-23-871 % similar Medroxyprogesterone520-85-471 % similar Megestrol acetate595-33-560 % similar Chlormadinone acetate302-22-759 % similar Nomegestrol acetate58652-20-355 % similar Hydroxyprogesterone caproate630-56-853 % similar 17β-Hydroxyprogesterone604-09-148 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Same formula

Bufalin465-21-4

Elsewhere

PubChem CAS Common Chemistry NIST WebBook