N-Hydroxysuccinimide

C4H5NO3CAS 6066-82-6115.09 g/mol

Open in Covalent MOL file
OONOH
AmideLactam

Properties

Molecular formula
C4H5NO3
Molar mass
115.09 g/mol
Exact mass
115.0269 Da
Melting point
97–98 °C
logP
-0.48Crippen estimate
Polar surface area
57.6 Ų
H-bond donors / acceptors
1 / 3
Rotatable bonds
0

Hazards

Warning
Irritant (GHS07)

Aggregated from 182 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501

Identifiers

CAS number
6066-82-6
SMILES
O=C1CCC(=O)N1O
InChIKey
NQTADLQHYWFPDB-UHFFFAOYSA-N
InChI
InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

9 names
  • 2,5-Pyrrolidinedione, 1-hydroxy-
  • Succinimide, N-hydroxy-
  • 1-Hydroxy-2,5-pyrrolidinedione
  • Hydroxysuccinimide
  • 1-Hydroxysuccinimide
  • N-Hydroxy-2,5-dioxopyrrolidine
  • NSC 74335
  • N-Hydroxypyrrolidine-2,5-dione
  • NHS

Work with N-Hydroxysuccinimide

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

N-Methylsuccinimide1121-07-943 % similar N-Bromosuccinimide128-08-543 % similar N-Chlorosuccinimide128-09-643 % similar N-Hydroxymaleimide4814-74-843 % similar N-Iodosuccinimide516-12-143 % similar N-[2-Hydroxyethyl]succinimide18190-44-842 % similar Di(succinimido) carbonate74124-79-139 % similar N,N-Dimethylsuccinamic acid2564-95-637 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Same formula

Alanine N-carboxyanhydride2224-52-4 Maleamic acid557-24-4

Elsewhere

PubChem CAS Common Chemistry NIST WebBook Wikipedia