Acetazolamide

C4H6N4O3S2CAS 59-66-5222.24 g/mol

Open in Covalent MOL file
OHNNNSNH2OOS
Sulfonamide

Properties

Molecular formula
C4H6N4O3S2
Molar mass
222.24 g/mol
Exact mass
221.9881 Da
Melting point
260.5 °C
Water solubility
< 1 g/L (22.2 °C)
logP
-0.21Crippen estimate
Polar surface area
118.5 Ų
H-bond donors / acceptors
2 / 6
Rotatable bonds
2

Hazards

Warning
Irritant (GHS07)Health Hazard (GHS08)

Aggregated from 153 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P264, P264+P265, P280, P302+P352, P305+P351+P338, P318, P321, P332+P317, P337+P317, P362+P364, P405, P501

Identifiers

CAS number
59-66-5
SMILES
CC(O)=Nc1nnc(S(N)(=O)=O)s1
InChIKey
BZKPWHYZMXOIDC-UHFFFAOYSA-N
InChI
InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

41 names · show all
  • Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-
  • Acetamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-
  • N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
  • 5-Acetamide-1,3,4-thiadiazole-2-sulfonamide
  • 2-Acetamido-5-sulfonamido-1,3,4-thiadiazole
  • Diacarb
  • Diamox
  • Diuramid
  • Edemox
  • Fonurit
  • Natrionex
  • Nephramide
  • Phonurit
  • 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide
  • 2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide
  • Cidamex
  • Acetamox
  • Nephramid
  • Diutazol
  • Diluran
  • Glaupax
  • Donmox
  • Glupax
  • Dehydratin
  • 5-Acetylamino-1,3,4-thiadiazol-2-ylsulfonamide
  • Diakarb
  • Acetazolamid
  • 5-Acetamido-1,3,4-thiodiazole-2-sulfonamide
  • Eumicton
  • Diuramide
  • L 579486
  • N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
  • 2-Acetamido-1,3,4-thiadiazole-5-sulfonamide
  • Atenezol
  • Diuriwas
  • Defiltran
  • Didoc
  • Carbonic anhydrase inhibitor 6063
  • Diureticum-holzinger
  • NSC 145177
  • AZM

Work with Acetazolamide

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Acetazolamide-D31189904-01-5Labelled

Similar compounds

Acetylsulfanilamide121-61-949 % similar 2-Acetylamino-5-mercapto-1,3,4-thiadiazole32873-56-649 % similar N-[2-[4-(Aminosulfonyl)phenyl]ethyl]acetamide41472-49-540 % similar Methazolamide554-57-436 % similar N-2-Thiazolylacetamide2719-23-536 % similar 2-(Acetylamino)-5-nitrothiazole140-40-935 % similar N-[(4S,6S)-2-(Aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno[2,3-b]thiopyran-4-yl]acetamide147200-03-134 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

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