chempirical

Hydrochlorothiazide

C7H8ClN3O4S2CAS 58-93-5297.73 g/mol

Open in Covalent MOL file
NH2SOOClNHNHSOO
Aryl halideSecondary amineSulfonamide

Properties

Molecular formula
C7H8ClN3O4S2
Molar mass
297.73 g/mol
Exact mass
296.9645 Da
Melting point
273–275 °C
logP
-0.35Crippen estimate
Polar surface area
118.4 Ų
H-bond donors / acceptors
3 / 5
Rotatable bonds
1

Identifiers

CAS number
58-93-5
SMILES
NS(=O)(=O)c1cc2c(cc1Cl)NCNS2(=O)=O
InChIKey
JZUFKLXOESDKRF-UHFFFAOYSA-N
InChI
InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

90 names · show all
  • Hidril
  • 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide
  • Su 5879
  • Aquarius
  • 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
  • 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
  • Chlorosulthiadil
  • Dichlotride
  • Diclotride
  • Dihydrochlorothiazide
  • 3,4-Dihydrochlorothiazide
  • Esidrex
  • Esidrix
  • HCTZ
  • HCZ
  • Hydril
  • Hydro-diuril
  • Hydrosaluric
  • Hypothiazid
  • Hypothiazide
  • Oretic
  • Vetidrex
  • Hypothiazide (C7H8ClN3O4S2)
  • Nefrix
  • Hydrochlorthiazide
  • 6-Chloro-7-sulfamoyl-3,4-dihydrobenzo-1,2,4-thiadiazine-1,1-dioxide
  • Hydrochlorothiazid
  • Dihydrochlorothiazidum
  • Dichlotiazid
  • Disalunil
  • Hidrochlortiazid
  • Idrotiazide
  • Drenol
  • Megadiuril
  • Hydro-aquil
  • Hidrotiazida
  • Hydrodiuretic
  • Dihydrochlorurite
  • Dihydrochlorurit
  • Microzide
  • Hidrenox
  • Nefrol
  • Neoflumen
  • Dichlozid
  • Diuret-P
  • Newtolide
  • Hidrosaluretil
  • Apo-hydro
  • Natrimax
  • Dichlothiazide
  • Servithiazid
  • Urirex
  • Tandiur
  • Hydro-T
  • Hydrex-semi
  • HCT
  • Didralin
  • Hydro par
  • Carozide
  • Idrodiuvis
  • Hydrozide
  • Hydrochlorzide
  • Manschitt
  • Zide
  • Hydrocot
  • Diurizid
  • Aquazide H
  • Clothia
  • Maschitt
  • Disothiazide
  • Diurex
  • Hydrex
  • Pantemon
  • Chlorsulthiadil
  • Acuretic
  • Ziac
  • Lotensin HCT
  • Caplaril
  • HH 25/25
  • Thiuretic
  • Unipres
  • HH 50/50
  • Timolide
  • Lopressor HCT
  • Apresazide
  • NSC 53477
  • Aquazide
  • Clorana
  • Trilopace H

Work with Hydrochlorothiazide

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

Trichlormethiazide133-67-554 % similar Cyclopenthiazide742-20-152 % similar 4-Amino-6-chloro-1,3-benzenedisulfonamide121-30-249 % similar Chlorothiazide58-94-648 % similar Methyclothiazide135-07-944 % similar 2-Chlorobenzenesulfonamide6961-82-641 % similar 4-Amino-2-chloro-5-hydroxybenzenesulfonamide41606-65-941 % similar 5-(Aminosulfonyl)-2,4-dichlorobenzoic acid2736-23-440 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Elsewhere

PubChem CAS Common Chemistry NIST WebBook