Sulfamethazine

C12H14N4O2SCAS 57-68-1278.33 g/mol

Open in Covalent MOL file
NNHSOOH2NN
Primary amineSulfonamide

Properties

Molecular formula
C12H14N4O2S
Molar mass
278.33 g/mol
Exact mass
278.0837 Da
Density
1.47 g/mL
Melting point
198.5 °C
pKa
2.07, 2.65 (aromatic amine), 7.65 (sulfonamide nitrogen)
Water solubility
< 1 g/L (20.5 °C)
logP
1.48Crippen estimate
Polar surface area
98.0 Ų
H-bond donors / acceptors
2 / 5
Rotatable bonds
3

Hazards

Warning
Irritant (GHS07)

Aggregated from 48 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364

Identifiers

CAS number
57-68-1
SMILES
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
InChIKey
ASWVTGNCAZCNNR-UHFFFAOYSA-N
InChI
InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

Weigh it out

Type any one amount. The others follow from the molar mass and density.

Names and synonyms

60 names · show all
  • Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-
  • Sulfanilamide, N1-(4,6-dimethyl-2-pyrimidinyl)-
  • 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide
  • Azolmetazin
  • Cremomethazine
  • Diazil
  • N1-(4,6-Dimethyl-2-pyrimidinyl)sulfanilamide
  • N1-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide
  • 4,6-Dimethyl-2-sulfanilamidopyrimidine
  • Dimezathine
  • Mermeth
  • Neazina
  • Pirmazin
  • Sulfadimerazine
  • Sulfadimesine
  • Sulfadimethyldiazine
  • Sulfadimethylpyrimidine
  • Sulfadimezine
  • Sulfadimidine
  • Sulfadine
  • Sulfamethiazine
  • 2-Sulfanilamido-4,6-dimethylpyrimidine
  • Sulfodimesin
  • Sulphadimethylpyrimidine
  • Sulphadimidine
  • Vertolan
  • Sulfodimezine
  • Superseptil
  • Spanbolet
  • Superseptyl
  • Sulfadimesin
  • A 502
  • Sulphamethasine
  • 2-(p-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine
  • N-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide
  • Sulphamethazine
  • Sulfadimezin
  • Sulphodimezine
  • Sulfadimidin
  • Kelametazine
  • Diazyl
  • Sulphamezathine
  • Sulphamidine
  • Neasina
  • 2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine
  • BN 2409
  • Calfspan
  • S-Dimidine
  • SulfaSURE SR Bolus
  • Sulka K boluses
  • Dimidin R
  • DiazilSulfadine
  • Calfspan tablets
  • NSC 67457
  • NSC 683529
  • Sustain III
  • Panazin
  • 2-(4-Aminobenzenesulfonylamino)-4,6-dimethylpyrimidine
  • 4-Amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
  • SMZ

Work with Sulfamethazine

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Sulfadimidine sodium1981-58-4Salt

Similar compounds

Sulfamerazine127-79-772 % similar Sulfadiazine68-35-956 % similar 4,4′-Diaminobenzenesulfonanilide16803-97-753 % similar N-(4-Aminophenyl)-4-methylbenzenesulfonamide6380-08-153 % similar Sulfamethoxydiazine651-06-952 % similar Sulfamethoxazole723-46-652 % similar Sulfamethizole144-82-150 % similar Sulfadimethoxine122-11-249 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Same formula

Sulfisomidine515-64-0

Elsewhere

PubChem CAS Common Chemistry NIST WebBook