Meclizine

C25H27ClN2CAS 569-65-3390.96 g/mol

Open in Covalent MOL file
NNCl
Aryl halideTertiary amine

Properties

Molecular formula
C25H27ClN2
Molar mass
390.96 g/mol
Exact mass
390.1863 Da
Boiling point
230 °C (at 2 Torr)
logP
5.56Crippen estimate
Polar surface area
6.5 Ų
H-bond donors / acceptors
0 / 2
Rotatable bonds
5

Hazards

Warning
Irritant (GHS07)

Aggregated from the ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P264+P265, P280, P305+P351+P338, P337+P317

Identifiers

CAS number
569-65-3
SMILES
Cc1cccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c1
InChIKey
OCJYIGYOJCODJL-UHFFFAOYSA-N
InChI
InChI=1S/C25H27ClN2/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23/h2-13,18,25H,14-17,19H2,1H3

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

22 names · show all
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-
  • Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-
  • 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
  • U.C.B. 5062
  • Ancolan
  • Bonine
  • 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine
  • 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)piperazine
  • Histametizyne
  • neo-Istafene
  • Meclozine
  • Navicalm
  • Parachloramine
  • Postafene
  • 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)piperazine
  • Sabari
  • Suprimal
  • Ravelon
  • Vomisseis
  • (±)-Meclizine
  • NSC 169189
  • 1-[(4-Chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine hydrate

Work with Meclizine

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Meclizine hydrochloride1104-22-9Salt Meclizine dihydrochloride monohydrate31884-77-2Salt

Similar compounds

Buclizine hydrochloride129-74-862 % similar 4-((4-Chlorophenyl)phenylmethyl)-1-piperazineethanol109806-71-559 % similar (-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine130018-88-153 % similar (-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine300543-56-053 % similar Norchlorcyclizine303-26-453 % similar (±)-Hydroxyzine68-88-252 % similar 3-Methylbenzylpiperazine5321-48-251 % similar Hydroxyzine hydrochloride2192-20-349 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

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